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胎盘植入的产前诊断:超声检查还是磁共振成像?

Prenatal diagnosis of placenta accreta: sonography or magnetic resonance imaging?

作者信息

Dwyer Bonnie K, Belogolovkin Victoria, Tran Lan, Rao Anjali, Carroll Ian, Barth Richard, Chitkara Usha

机构信息

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Stanford University, Stanford, California, USA.

出版信息

J Ultrasound Med. 2008 Sep;27(9):1275-81. doi: 10.7863/jum.2008.27.9.1275.

Abstract

OBJECTIVE

The purpose of this study was to compare the accuracy of transabdominal sonography and magnetic resonance imaging (MRI) for prenatal diagnosis of placenta accreta.

METHODS

A historical cohort study was undertaken at 3 institutions identifying women at risk for placenta accreta who had undergone both sonography and MRI prenatally. Sonographic and MRI findings were compared with the final diagnosis as determined at delivery and by pathologic examination.

RESULTS

Thirty-two patients who had both sonography and MRI prenatally to evaluate for placenta accreta were identified. Of these, 15 had confirmation of placenta accreta at delivery. Sonography correctly identified the presence of placenta accreta in 14 of 15 patients (93% sensitivity; 95% confidence interval [CI], 80%-100%) and the absence of placenta accreta in 12 of 17 patients (71% specificity; 95% CI, 49%-93%). Magnetic resonance imaging correctly identified the presence of placenta accreta in 12 of 15 patients (80% sensitivity; 95% CI, 60%-100%) and the absence of placenta accreta in 11 of 17 patients (65% specificity; 95% CI, 42%-88%). In 7 of 32 cases, sonography and MRI had discordant diagnoses: sonography was correct in 5 cases, and MRI was correct in 2. There was no statistical difference in sensitivity (P = .25) or specificity (P = .5) between sonography and MRI.

CONCLUSIONS

Both sonography and MRI have fairly good sensitivity for prenatal diagnosis of placenta accreta; however, specificity does not appear to be as good as reported in other studies. In the case of inconclusive findings with one imaging modality, the other modality may be useful for clarifying the diagnosis.

摘要

目的

本研究旨在比较经腹超声检查和磁共振成像(MRI)对胎盘植入产前诊断的准确性。

方法

在3家机构进行了一项历史性队列研究,纳入有胎盘植入风险且产前均接受过超声检查和MRI检查的女性。将超声和MRI检查结果与分娩时及病理检查确定的最终诊断进行比较。

结果

共确定32例产前接受超声检查和MRI检查以评估胎盘植入的患者。其中,15例在分娩时确诊为胎盘植入。超声检查在15例患者中的14例正确识别出胎盘植入的存在(灵敏度93%;95%置信区间[CI],80%-100%),在17例患者中的12例正确识别出无胎盘植入(特异度71%;95%CI,49%-93%)。MRI在15例患者中的12例正确识别出胎盘植入的存在(灵敏度80%;95%CI,60%-100%),在17例患者中的11例正确识别出无胎盘植入(特异度65%;95%CI,42%-88%)。在32例病例中的7例,超声检查和MRI诊断不一致:超声检查在5例中正确,MRI在2例中正确。超声检查和MRI在灵敏度(P = 0.25)或特异度(P = 0.5)方面无统计学差异。

结论

超声检查和MRI对胎盘植入的产前诊断均具有相当好的灵敏度;然而,特异度似乎不如其他研究报道的那样好。在一种成像方式检查结果不明确的情况下,另一种成像方式可能有助于明确诊断。

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