Tronina Svetlana A, Bobrova Nadiya F, Khrinenko Valentina P
The Filatov Institute of Eye Diseases and Tissue Therapy, Odessa, Ukraine.
Orbit. 2008;27(4):249-57. doi: 10.1080/01676830802250101.
To analyze the results of application of combined surgical treatment in different forms of hemangioma in infants.
One hundred seventy-four children with different forms of orbital and periorbital hemangiomas aged 1-16 months (mean age 5.2 + 1.97 months) were operated on at the pediatric ophthalmology department. Fast growth of hemangioma, both superficial (intradermal) and deep (subdermal and orbital) localization, significant deformity of eyelids, with narrowing of eye fissure were the indications for surgical treatment. The combined-staged method, including cryosurgery of superficial intradermal lesions and surgical excision of subdermal and/or orbital parts of the tumor in different combinations depending on the form and depth of hemangioma spreading, was applied.
Usage of cryodestruction usually on the first stage of treatment allowed gentle scarring of the angiomatously changed skin areas. Surgical excision of the deep part of the tumor eliminated disfigurement and visual axis occlusion, avoiding amblyopia development. Good cosmetic and anatomic result was achieved in 90.4% of cases.
Combined surgical method of treatment of progressive capillary hemangiomas by using cryosurgery and surgical excision in infants allows the choice of optimum tactics depending on features of the course and clinical picture in each individual case and provides achievement of high cosmetic and functional result of treatment. The early beginning of treatment in cases of fast progressing of the tumor allows prevention of extensive skin affection and amblyopia development.
分析联合手术治疗婴儿不同类型血管瘤的应用结果。
174例年龄在1 - 16个月(平均年龄5.2 + 1.97个月)的不同类型眼眶及眶周血管瘤患儿在小儿眼科接受手术。血管瘤快速生长,包括浅表(皮内)和深部(皮下及眼眶)定位,眼睑明显畸形伴睑裂狭窄是手术治疗的指征。采用联合分期方法,根据血管瘤扩展的形式和深度,以不同组合方式对浅表皮内病变进行冷冻手术,并对肿瘤的皮下和/或眼眶部分进行手术切除。
通常在治疗的第一阶段使用冷冻破坏可使血管瘤病变皮肤区域形成轻微瘢痕。肿瘤深部的手术切除消除了畸形并避免了视轴遮挡,防止了弱视的发生。90.4%的病例获得了良好的美容和解剖学效果。
婴儿期采用冷冻手术和手术切除联合治疗进行性毛细血管瘤的手术方法,可根据每个病例的病程特点和临床表现选择最佳策略,并实现治疗的高美容和功能效果。在肿瘤快速进展的情况下早期开始治疗可预防广泛的皮肤受累和弱视的发生。