Dane Cem, Dane Banu, Cetin Ahmet, Erginbas Murat, Tatar Zeynep
Department of Gynecology and Obstetrics Clinic, Haseki Training and Research Hospital, Istanbul, Turkey.
Am J Clin Dermatol. 2008;9(5):333-5. doi: 10.2165/00128071-200809050-00008.
Fibroepithelial stromal polyps of the vulvovaginal region display a wide range of morphologic appearances. This morphologic spectrum allows the correct diagnosis to be made in some cases but when histology reveals unusual features, the lesion may be misinterpreted as malignant. We present a case of a 35-year-old woman with psoriasis who developed a 15-cm polypoid lesion localized in the left labium. The labial lesion was resected and no recurrence was detected 12 months after the initial treatment. Histologically, the lesion exhibited the characteristics of a fibroepithelial stromal polyp with focal myxoid areas and underlying vulval psoriasis disease. The clinical, microscopic, and immunohistochemical findings of this case suggest a fibroepithelial polyp of the vulva. This vulval lesion represents a unique example of giant fibroepithelial stromal polyp developed in association with psoriasis.
外阴阴道区域的纤维上皮性间质息肉具有广泛的形态学表现。这种形态学谱在某些情况下有助于做出正确诊断,但当组织学显示出不寻常特征时,该病变可能会被误诊为恶性。我们报告一例35岁患有银屑病的女性,其左侧阴唇出现一个15厘米的息肉样病变。唇部病变被切除,初始治疗12个月后未发现复发。组织学上,该病变表现为纤维上皮性间质息肉的特征,伴有局灶性黏液样区域以及潜在的外阴银屑病。该病例的临床、显微镜检查和免疫组化结果提示为外阴纤维上皮性息肉。这种外阴病变是与银屑病相关的巨大纤维上皮性间质息肉的一个独特例子。