复发性外阴巨大纤维上皮性间质息肉伴先天性淋巴水肿。
Recurrent giant fibroepithelial stromal polyp of the vulva associated with congenital lymphedema.
作者信息
Orosz Zsolt, Lehoczky Ottó, Szoke János, Pulay Tamás
机构信息
Department of Oncopathology, National Institute of Oncology, Budapest, Hungary.
出版信息
Gynecol Oncol. 2005 Jul;98(1):168-71. doi: 10.1016/j.ygyno.2005.01.020.
BACKGROUND
The relatively site-specific mesenchymal lesions of the vulvovaginal region can exhibit superficially overlapping histological features and can be diagnostically challenging. Fibroepithelial stromal polyp is generally an easily recognizable entity, but certain cases cause differential diagnostic problems.
CASE
We present a case of a 16-year-old girl with a 10-cm polypoid lesion localized to the left labium. The patient has therapy resistant congenital lymphedema localized to the left arm and leg. The labial lesion was resected and recurred after 12 months and 6 years following the initial treatment. Histologically, it exhibited characteristics of a fibroepithelial stromal polyp with scattered bizarre multinucleated giant cells and ectatic tortuous lymphatic spaces.
CONCLUSION
This vulvar lesion represents a unique example of giant fibroepithelial stromal polyp developed in association with Nonne-Milroy-Meiges syndrome.
背景
外阴阴道区域相对具有部位特异性的间质性病变可表现出表面上重叠的组织学特征，在诊断上具有挑战性。纤维上皮性间质息肉通常是一种易于识别的实体，但某些病例会引起鉴别诊断问题。
病例
我们报告一例16岁女孩，其左阴唇有一个10厘米的息肉样病变。患者患有局限于左臂和左腿的对治疗耐药的先天性淋巴水肿。唇部病变切除后，在初始治疗后的12个月和6年复发。组织学上，它表现出纤维上皮性间质息肉的特征，伴有散在的奇异多核巨细胞和扩张迂曲的淋巴管腔隙。
结论
该外阴病变代表了与诺内-米尔罗伊-梅热综合征相关的巨大纤维上皮性间质息肉的一个独特例子。
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