Carter Lachlan M, Brizman Eitan
Maxillofacial Surgery, Leeds Dental Institute, Clarendon Way, Leeds, UK.
Head Face Med. 2008 Aug 21;4:19. doi: 10.1186/1746-160X-4-19.
Wegener's granulomatosis (WG) is a multi-system disease, characterised by the triad of necrotising granulomata affecting the upper and lower respiratory tracts, disseminated vasculitis and glomerulonephritis. Oral lesions are associated with up to 50% of cases, although are rare as a presenting feature. The most common oral lesions associated with WG are ulceration and strawberry gingivitis. We review the literature regarding oral manifestations of WG and present a case of lingual infarction, an extremely rare oral lesion associated with WG, in a severe, rapidly progressive and ultimately fatal form of the disease.
韦格纳肉芽肿(WG)是一种多系统疾病,其特征为影响上、下呼吸道的坏死性肉芽肿、播散性血管炎和肾小球肾炎三联征。口腔病变在高达50%的病例中出现,尽管作为首发特征较为罕见。与韦格纳肉芽肿相关的最常见口腔病变是溃疡和草莓样牙龈炎。我们回顾了有关韦格纳肉芽肿口腔表现的文献,并报告了一例舌梗死病例,这是一种与韦格纳肉芽肿相关的极其罕见的口腔病变,该病例呈现为该病严重、快速进展且最终致命的形式。