Filocamo Giovanni, Buoncompagni Antonella, Viola Stefania, Loy Anna, Malattia Clara, Ravelli Angelo, Martini Alberto
Pediatria II IRCCS G. Gaslini e Dipartimento di Pediatria, Università di Genova, Italy.
J Pediatr. 2008 Sep;153(3):432-4. doi: 10.1016/j.jpeds.2008.04.049.
Four children with Takayasu's arteritis were treated with tumor necrosis factor antagonists because of disease relapse during conventional therapy or as a first-line agent. Two patients went into remission; in the other 2, the response was partial. Anti-tumor necrosis factor agents can have a role in the treatment of Takayasu's arteritis; further controlled studies are required.
4名大动脉炎患儿因在传统治疗期间疾病复发或作为一线治疗药物而接受肿瘤坏死因子拮抗剂治疗。2例患者病情缓解；另外2例部分缓解。抗肿瘤坏死因子药物在大动脉炎治疗中可能起作用；还需要进一步的对照研究。
