Hartmann A, Olbrich H G, Hopf R, Schneider M, Lösse B, Kaltenbach M
Abt. für Kardiologie, Zentrum Innere Medizin, Universität Frankfurt.
Z Kardiol. 1991 May;80(5):338-43.
Five patients with hypertrophic cardiomyopathy developed left-ventricular dilatation and congestive heart failure during an observation period of 16-29 years. In one patient cardiac transplantation had to be performed. The initial predominant symptoms of outflow-tract obstruction and diastolic dysfunction developed into progressive left-ventricular systolic failure. The question of whether this is a well-defined subgroup of patients with hypertrophic cardiomyopathy, or whether hypertrophic cardiomyopathy turns into a phase of left-ventricular dilatation and failure after some years remains to be elucidated by long-term studies.
在16至29年的观察期内，5例肥厚型心肌病患者出现左心室扩张和充血性心力衰竭。其中1例患者不得不接受心脏移植。最初以流出道梗阻和舒张功能障碍为主的症状发展为进行性左心室收缩功能衰竭。这是肥厚型心肌病患者中一个明确的亚组，还是肥厚型心肌病在数年后转变为左心室扩张和衰竭阶段，这一问题仍有待长期研究阐明。
