Song Wei-Liang, Wang Zhen-Jun, Zheng Yi, Yang Xin-Qing, Peng Ya-Ping
Department of General Surgery, Chaoyang Hospital of Capital Medicine University, Beijing 100020, China.
World J Gastroenterol. 2008 Aug 14;14(30):4791-4. doi: 10.3748/wjg.14.4791.
To investigate a new technique of the anorectal fistula treatment with acellular extracellular matrix (AEM).
Thirty patients with anorectal fistula were treated with AEM. All fistula tracts and primary openings were identified using conventional fistula probe. All tracts were curetted with curet and irrigated with hydrogen peroxide and metronidazole. The AEM was pulled into the fistula tract from secondary to primary opening. The material was secured at the level of the primary opening. The excess AEM was trimmed at skin level at the secondary opening.
All of the 30 patients had successful closure of their fistula after a 7-14 d follow-up. The healing rate of anal fistula in treatment group was 100%. The ache time, healing time and anal deformation of treatment group were obviously superior to traditional surgical methods.
Using AEM anal fistula plug in treatment that causes the anorectal fistula is safe and successful in 100% of patients. It can reduce pain, shorten disease course and protect anal function.
探讨应用脱细胞细胞外基质（AEM）治疗肛瘘的新技术。
30例肛瘘患者接受AEM治疗。使用传统肛瘘探针确定所有瘘管和原发开口。所有瘘管用刮匙刮除，并用过氧化氢和甲硝唑冲洗。将AEM从继发开口向原发开口拉入瘘管。材料在原发开口处固定。多余的AEM在继发开口处的皮肤水平修剪。
30例患者在7 - 14天随访后肛瘘均成功闭合。治疗组肛瘘愈合率为100%。治疗组的疼痛时间、愈合时间和肛门变形情况明显优于传统手术方法。
使用AEM肛瘘封堵术治疗肛瘘对100%的患者安全且成功。它可减轻疼痛、缩短病程并保护肛门功能。
