Electrically-induced osteogenesis in external fixation treatment.

This animal model experiment is performed to evaluate how bipolar direct current of 20 microamp. affects osteogenesis once external fixation treatment is applied in different forms: stabilization, distraction, and compression. In all cases a secondary healing, typical of external fixation treatment, was found; but a more mineralized callus and an increase in osteoprogenitor cell proliferation and differentiation were obtained through the use of electrical stimulation especially in the compression group.