Zorowka P, Heinemann M, Kraft E
Klinik für Kommunikationsstörungen, Johannes-Gutenberg Universität Maínz.
Laryngorhinootologie. 1991 Jun;70(6):312-5. doi: 10.1055/s-2007-998044.
In 1987 and 1988 Nickisch et al. discussed the effect of infusions of prednisolone, pentoxifylline and, partially, piracetam in Ringer lactate solvent on progressive sensorineural hearing loss in childhood and adolescence. Time of observations was 4 years. Unfortunately long-term investigations could not confirm the initially good therapeutic results of 1987/88. In 35% were found permanently and in 12.5% temporarily better auditory thresholds after infusion. The loss of progressive sensorineural hearing in childhood usually takes a fateful course that can hardly be influenced. As is the case with adults, good therapeutic results can most probably be achieved by infusions starting close to the event, i.e. within 48 hours.
1987年和1988年，尼基施等人探讨了在乳酸林格氏液溶剂中输注泼尼松龙、己酮可可碱以及部分吡拉西坦对儿童和青少年进行性感音神经性听力损失的影响。观察时间为4年。遗憾的是，长期研究未能证实1987/88年最初良好的治疗效果。输注后，35%的患者永久性地、12.5%的患者暂时性地出现了更好的听阈。儿童进行性感音神经性听力损失通常会发展到灾难性的程度，几乎难以受到影响。与成年人一样，很可能在事件发生后不久，即48小时内开始输注，才能取得良好的治疗效果。
