Meoli F G, Kopitnik N L
Department of Surgery, University of Medicine and Dentistry of New Jersey--School of Osteopathic Medicine, Stratford.
J Am Osteopath Assoc. 1991 Jun;91(6):606-13.
Hemangiopericytoma is an extremely rare soft tissue tumor of the pericytes that surround the walls of blood vessels. The lesion is characterized by proliferation of the pericytes above the basement membrane. The microscopic features of the hemangiopericytoma can often be demonstrated by reticulin staining. Clinical presentation can vary. The lesion has been found in any number of anatomic locations. Occurrence in breast tissue, however, has been strikingly rare. Most lesions are benign. However, they can be aggressive and can recur at distant sites. Malignant varieties have been reported. In breast tissue, the most difficult aspect of the diagnosis appears to be that the tumor grossly, and to some extent microscopically, resembles cystosarcoma phylloides, particularly in the malignant degenerative form of the latter disease. Most diagnostic methods for evaluating the tumor fail to produce a definitive diagnosis. Microscopic confirmation is perhaps the only method by which definitive diagnosis can be made. Treatment consists of wide excision and careful clinical follow-up. A case history and a review of the literature concerning this lesion are included here.
血管外皮细胞瘤是一种极其罕见的起源于围绕血管壁的周细胞的软组织肿瘤。该病变的特征是基底膜上方的周细胞增殖。血管外皮细胞瘤的微观特征通常可用网状纤维染色显示。临床表现可能各异。该病变可发生于任何解剖部位。然而，在乳腺组织中发生极为罕见。大多数病变是良性的。然而，它们可能具有侵袭性，并且可在远处部位复发。已有恶性类型的报道。在乳腺组织中，诊断最困难的方面似乎是该肿瘤在大体上以及在某种程度上在显微镜下类似于叶状囊肉瘤，特别是后者疾病的恶性退变形式。大多数评估该肿瘤的诊断方法都无法做出明确诊断。显微镜下确诊可能是做出明确诊断的唯一方法。治疗包括广泛切除和仔细的临床随访。本文包含一个病例报告以及有关该病变的文献综述。
