原发性乳腺癌的分期程序

Staging procedures in primary breast cancer.

作者信息

Müller Daniela, Köhler Günter, Ohlinger Ralf

机构信息

Department of Obstetrics and Gynaecology, Ernst-Moritz-Arndt University, Greifswald, Germany.

出版信息

Anticancer Res. 2008 Jul-Aug;28(4C):2397-400.

PMID:18751425

Abstract

BACKGROUND

In consideration of increasing incidence by introduction of screening mammography, the prevalence of distant metastases and necessity of staging procedures in early breast cancer should be proved.

PATIENTS AND METHODS

A retrospective review was undertaken of 466 patients with newly diagnosed breast cancer in the period from 2003 to 2006.

RESULTS

Distant metastases were found in 22 (4.8%) patients at the time of primary diagnosis of breast cancer. None of these patients had a tumour < or =1 cm and the percentage of metastatic disease increased with local extension (pT1 1.4%; pT2 7.9%; pT3 14.3%; pT4 23.1%; p<0.001) and nodal status (pN0 1.7%; pN1 3.8%; pN2 21.7%; pN3 17.6%; p<0.001)

CONCLUSION

Indication for bone scan, liver ultrasound and chest x-ray should be limited to patients with tumours >2 cm, or tumours >1 cm with lymph node involvement (N1-3).

摘要

背景

鉴于乳腺钼靶筛查的引入导致发病率上升，早期乳腺癌远处转移的患病率及分期程序的必要性应得到证实。

患者与方法

对2003年至2006年期间新诊断为乳腺癌的466例患者进行回顾性研究。

结果

在乳腺癌初诊时，22例（4.8%）患者发现有远处转移。这些患者中无一例肿瘤≤1 cm，转移疾病的百分比随局部扩展（pT1 1.4%；pT2 7.9%；pT3 14.3%；pT4 23.1%；p<0.001）和淋巴结状态（pN0 1.7%；pN1 3.8%；pN2 21.7%；pN3 17.6%；p<0.001）而增加。