Wasserberg Nir, Hamoui Nahid, Petrone Patrizio, Crookes Peter F, Kaufman Howard S
Division of Colorectal and Pelvic Floor Surgery, Department of Surgery, University of Southern California, Los Angeles, CA, USA.
Obes Surg. 2008 Dec;18(12):1563-6. doi: 10.1007/s11695-008-9658-9. Epub 2008 Aug 28.
One of the perceived disadvantages of the biliopancreatic diversion with duodenal switch operation is diarrhea. The aim of this study was to compare the bowel habits of patients after duodenal switch operation or Roux-en-Y gastric bypass.
A prospective comparative case series design was used. Forty-six patients who underwent duodenal switch (n=28) or gastric bypass (n=18) were asked to complete a daily diary for 14 days after losing least 50% of their excess body weight. Data were collected on number of bowel episodes, incontinence, urgency, stool consistency, and awakening from sleep to defecate. Background variables were recorded from the medical files.
The duodenal switch group was heavier (body mass index 53.5 vs 47.0 kg/m(2), p=0.03) and older (47.5 vs 41.0 years, p=NS) than the gastric bypass group. Median time to 50% excess body weight loss was 22 months in the duodenal switch group compared to 10.0 months in the gastric bypass group (p=0.001). Patients after duodenal switch surgery reported a median of 23.5 bowel episodes over the 14-day study period compared to 16.5 in the gastric bypass group (p=NS). There was no between-group differences in any of the other bowel parameters studied.
Although duodenal switch is associated with more bowel episodes than gastric bypass, the difference is not statistically significant. Bowel habits are similar in patients who achieve 50% estimated body weight loss with duodenal switch surgery or gastric bypass.
十二指肠转位术式的胆胰转流术被认为的缺点之一是腹泻。本研究的目的是比较十二指肠转位术或Roux-en-Y胃旁路术后患者的排便习惯。
采用前瞻性对比病例系列设计。46例行十二指肠转位术(n = 28)或胃旁路术(n = 18)的患者在减轻至少50%的超重体重后,被要求连续14天完成每日日志。收集排便次数、大便失禁、便急、大便性状以及因排便从睡眠中醒来等数据。从病历中记录背景变量。
十二指肠转位术组比胃旁路术组更重(体重指数53.5 vs 47.0 kg/m²,p = 0.03)且年龄更大(47.5 vs 41.0岁,p无统计学意义)。十二指肠转位术组减轻50%超重体重的中位时间为22个月,而胃旁路术组为10.0个月(p = 0.001)。在为期14天的研究期间,十二指肠转位术术后患者报告的排便次数中位数为23.5次,而胃旁路术组为16.5次(p无统计学意义)。在所研究的其他任何排便参数方面,两组之间均无差异。
尽管十二指肠转位术比胃旁路术的排便次数更多,但差异无统计学意义。十二指肠转位术或胃旁路术使预计体重减轻50%的患者排便习惯相似。