Sigurdsson Engilbert, Olafsdóttir Thórdís, Gottfredsson Magnús
Division of Psychiatry, Landspitali University Hospital, Reykjavik, Hringbraut, Iceland.
Nord J Psychiatry. 2008;62(5):374-8. doi: 10.1080/08039480801984156.
In Iceland, antidepressant sales figures rose from 8 Defined Daily Doses (DDD) per 1000 subjects in 1975 to 95 DDD/1000 in 2005. The aim of the study was to examine the views of adult Icelanders on antidepressant treatment and to identify the factors most influential in shaping their views, using cross-sectional national survey of views on antidepressant treatment in a randomly drawn sample of 2000 Icelanders aged 18-80 years old. Nine in 10 responders believed that regular exercise is an efficacious treatment for depression (92.6%) but supportive interviews came second (82.3%). Seven out of 10 believed that antidepressants are efficacious and the same proportion was willing to use antidepressants as a treatment for depression. The strongest predictor of this inclination was previous use of antidepressants (odds ratio, OR=6.9, 95% CI 3.4-13.8), followed by knowing someone well who had been treated with antidepressants (OR=2.3, 95% CI 1.6 to 3.3). Eight out of every 100 responders were taking antidepressants and further 8.3% had previously been on antidepressants for at least 6 weeks. Among past users of antidepressants, 77% felt that the benefits of therapy had outweighed the disadvantages. More knowledge on antidepressants was associated (chi-squared test=9.96, df=2, P=0.007) with willingness to use them. The majority of adult Icelanders are willing to use antidepressants for depression. The factors influencing their views most strongly are subjects' own experience and the experience of close friends or relatives as users.
在冰岛，抗抑郁药的销售数据从1975年每1000人8限定日剂量（DDD）上升至2005年的每1000人95 DDD。本研究的目的是通过对2000名年龄在18至80岁的冰岛人进行随机抽样的全国性横断面调查，了解成年冰岛人对抗抑郁治疗的看法，并确定最能影响其看法的因素。十分之九的受访者认为定期锻炼是治疗抑郁症的有效方法（92.6%），但支持性访谈位居第二（82.3%）。十分之七的人认为抗抑郁药有效，同样比例的人愿意使用抗抑郁药来治疗抑郁症。这种倾向的最强预测因素是之前使用过抗抑郁药（优势比，OR = 6.9，95%置信区间3.4 - 13.8），其次是熟知有人接受过抗抑郁药治疗（OR = 2.3，95%置信区间1.6至3.3）。每100名受访者中有8人正在服用抗抑郁药，另有8.3%的人之前服用抗抑郁药至少6周。在过去使用过抗抑郁药的人中，77%认为治疗的益处大于弊端。对抗抑郁药了解更多与愿意使用它们相关（卡方检验 = 9.96，自由度 = 2，P = 0.007）。大多数成年冰岛人愿意使用抗抑郁药治疗抑郁症。最强烈影响他们看法的因素是受试者自身的经历以及亲密朋友或亲属作为使用者的经历。
