Schneider Diane L
University of California, San Diego, La Jolla, CA 92093, USA.
Curr Osteoporos Rep. 2008 Sep;6(3):100-7. doi: 10.1007/s11914-008-0018-4.
The incidence of osteoporotic fractures increases with advancing age and is associated with significant health care expenditures, particularly related to hip fractures and loss of quality of life. Unfortunately, few studies have included subjects 80 years of age and older to help guide management of elderly patients who are living in the community or in long-term care facilities. Treating this age group encompasses the same general measures and pharmacologic therapies as in younger adults. Focusing on fall prevention and adequate vitamin D is essential. All prevention strategies in the elderly for fracture risk reduction should include simple vitamin D and calcium supplementation. However, for those at high risk of fracture, adding pharmacologic therapy should be considered. This article reviews recent research findings of general measures and pharmacologic therapy that are applicable to managing osteoporosis in the elderly.
骨质疏松性骨折的发生率随年龄增长而增加，且与高额的医疗保健支出相关，尤其是与髋部骨折及生活质量下降有关。遗憾的是，很少有研究纳入80岁及以上的受试者，以帮助指导对社区或长期护理机构中老年患者的管理。治疗这一年龄组所采用的一般措施和药物治疗与年轻成年人相同。注重预防跌倒和充足的维生素D至关重要。老年人所有降低骨折风险的预防策略都应包括简单的维生素D和钙补充。然而，对于骨折高危人群，应考虑增加药物治疗。本文综述了适用于老年骨质疏松症管理的一般措施和药物治疗的最新研究结果。
