粘质沙雷氏菌在糖尿病小鼠尿路感染发病机制中的黏附作用。
Adherence of Serratia marcescens in the pathogenesis of urinary tract infections in diabetic mice.
作者信息
Obana Y, Shibata K, Nishino T
机构信息
Department of Microbiology, Kyoto Pharmaceutical University, Japan.
出版信息
J Med Microbiol. 1991 Aug;35(2):93-7. doi: 10.1099/00222615-35-2-93.
PMID:1875397
Abstract
The adherence of Serratia marcescens to bladder epithelial cells of mice with alloxan-induced diabetes was studied. S. marcescens adhered more strongly to the bladder epithelial cells of diabetic mice than to those of normal mice both in vitro and in vivo. The susceptibility of diabetic mice to urinary tract infection may be due to an increased adhesive capacity of bladder epithelial cells.
摘要
研究了粘质沙雷氏菌对用四氧嘧啶诱导糖尿病的小鼠膀胱上皮细胞的粘附情况。在体外和体内，粘质沙雷氏菌对糖尿病小鼠膀胱上皮细胞的粘附均比对正常小鼠膀胱上皮细胞的粘附更强。糖尿病小鼠对尿路感染的易感性可能归因于膀胱上皮细胞粘附能力的增强。
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