Pasch Andreas
Department of Nephrology and Hypertension, Inselspital, University of Bern, Bern, Switzerland.
Kidney Int. 2008 Sep;74(6):697-9. doi: 10.1038/ki.2008.321.
Yajima and co-workers investigated iliac bone biopsies taken before and after parathyroidectomy. They found enhanced de novo osteoid formation and mineral apposition at trabecular sites without signs of previous bone resorption. From this finding they conclude that 'minimodeling' contributes to the increase of bone volume following parathyroidectomy. This report refines our understanding of the compensatory mechanisms by which bone mass and possibly increased mechanical stability of the skeletal apparatus are regained after parathyroidectomy.
矢岛及其同事对甲状旁腺切除术前和术后采集的髂骨活检样本进行了研究。他们发现小梁部位有新的类骨质形成增强和矿物质沉积增加，且无先前骨吸收的迹象。基于这一发现，他们得出结论，“微塑型”有助于甲状旁腺切除术后骨量的增加。本报告完善了我们对甲状旁腺切除术后恢复骨量以及可能增加骨骼机械稳定性的代偿机制的理解。
