Campbell Katherine, Ali Unzila, Bahtiyar Mert
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut 06520-8063, USA.
Am J Perinatol. 2008 Oct;25(9):547-9. doi: 10.1055/s-0028-1085628. Epub 2008 Aug 28.
A 24-year-old woman in her third trimester of pregnancy presented with pulmonary symptoms consistent with acute chest syndrome (ACS). This was her first lifetime manifestation of sickle cell disease. Given the severity of ACS in a patient with no previous symptoms of the disease, we discuss the pathophysiology behind the development of ACS and the importance of practitioner vigilance during sickle cell patients' pregnancies.
一名处于妊娠晚期的24岁女性出现了与急性胸部综合征(ACS)相符的肺部症状。这是她镰状细胞病的首次发病表现。鉴于该疾病此前无症状的患者发生ACS的严重性,我们讨论了ACS发生背后的病理生理学以及在镰状细胞病患者妊娠期间医生保持警惕的重要性。