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[科尔维汀对不同基因型小鼠躯体疼痛的影响]

[Influence of korvityn on somatic pain in mice of different genotypes].

作者信息

Lymans'kyĭ Iu P, Bahats'ka O V, Hura O V, Nesin O M, Sushko B S, Tamarova Z A

出版信息

Fiziol Zh (1994). 2008;54(4):37-43.

PMID:18756773
Abstract

The influence of the intraperitoneal injection of quercetin solution (10 mg/kg) on painful reaction to the formalin test in male mice C57B1/6J (C57), CBA/CaLac (CBA) and in outbred albino mice was investigated. It was shown, that quercetin caused a various level of analgesia in the investigated animals. The highest level of analgesia (38,5 %) was observed in outbred white mice, the average - in mice C57 (27%) and the lowest - in mice CBA (13%).

摘要

研究了腹腔注射槲皮素溶液(10毫克/千克)对雄性C57B1/6J(C57)、CBA/CaLac(CBA)小鼠以及远交白化小鼠福尔马林试验疼痛反应的影响。结果表明,槲皮素在受试动物中引起了不同程度的镇痛作用。远交白色小鼠的镇痛水平最高(38.5%),C57小鼠次之(27%),CBA小鼠最低(13%)。

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