[氟化硅油对兔视网膜抗氧化状态的影响]

[Effect of fluorinated silicone oil on the rabbit retinal antioxidant status].

作者信息

Shkurenko I V, Shishkin M M, Dontsov A E, Sakina N L

出版信息

Vestn Oftalmol. 2008 Jul-Aug;124(4):41-4.

Abstract

The high-grade fluorinated silicone oil made in Russia was tested for its effect on the rabbit retinal antioxidant status. Experiments were made on 36 rabbits (72 eyes) undergoing replacement of the excised vitreous body with sterile 0.9 NaCl solution or with one of the study implants (fluorinated silicon oil, silicon oil, or perfluorodecahydronaphthalene) after subtotal vitrectomy. The impact of the study implants on the rabbit retinal antioxidant status was postoperattively investigated. The experimental findings suggest that the high-grade fluorinated silicon oil made in Russia may be used as an implant for short-term vitreous chamber tamponade.

摘要

对俄罗斯生产的高级氟化硅油对兔视网膜抗氧化状态的影响进行了测试。对36只兔子（72只眼）进行实验，在玻璃体大部分切除术后，用无菌0.9%氯化钠溶液或一种研究植入物（氟化硅油、硅油或全氟十氢萘）替代切除的玻璃体。术后研究植入物对兔视网膜抗氧化状态的影响。实验结果表明，俄罗斯生产的高级氟化硅油可作为短期玻璃体腔填塞的植入物。