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人类生殖性克隆与灵长类动物治疗性克隆:伦理辩论是否跟上了近期的科学进展?

Reproductive cloning in humans and therapeutic cloning in primates: is the ethical debate catching up with the recent scientific advances?

作者信息

Camporesi S, Bortolotti L

机构信息

European School of Molecular Medicine and University of Milan, Milan Italy.

出版信息

J Med Ethics. 2008 Sep;34(9):e15. doi: 10.1136/jme.2007.023879.

Abstract

After years of failure, in November 2007 primate embryonic stem cells were derived by somatic cellular nuclear transfer, also known as therapeutic cloning. The first embryo transfer for human reproductive cloning purposes was also attempted in 2006, albeit with negative results. These two events force us to think carefully about the possibility of human cloning which is now much closer to becoming a reality. In this paper we tackle this issue from two sides, first summarising what scientists have achieved so far, then discussing some of the ethical arguments in favour and against human cloning which are debated in the context of policy making and public consultation. Therapeutic cloning as a means to improve and save lives has uncontroversial moral value. As to human reproductive cloning, we consider and assess some common objections and failing to see them as conclusive. We do recognise, though, that there will be problems at the level of policy and regulation that might either impair the implementation of human reproductive cloning or make its accessibility restricted in a way that could become difficult to justify on moral grounds. We suggest using the time still available before human reproductive cloning is attempted successfully to create policies and institutions that can offer clear directives on its legitimate applications on the basis of solid arguments, coherent moral principles, and extensive public consultation.

摘要

经过多年的失败后,2007年11月通过体细胞细胞核移植(也称为治疗性克隆)获得了灵长类胚胎干细胞。2006年还首次尝试了用于人类生殖克隆目的的胚胎移植,不过结果是阴性的。这两件事迫使我们认真思考人类克隆的可能性,而现在它已比以往任何时候都更接近成为现实。在本文中,我们从两个方面来探讨这个问题,首先总结科学家们迄今为止所取得的成果,然后讨论在政策制定和公众咨询背景下引发争议的一些支持和反对人类克隆的伦理观点。治疗性克隆作为一种改善和拯救生命的手段具有无可争议的道德价值。至于人类生殖克隆,我们思考并评估了一些常见的反对意见,认为这些意见并不具有决定性。不过,我们确实认识到,在政策和监管层面将会出现一些问题,这些问题可能会阻碍人类生殖克隆的实施,或者使其获取受到限制,而这种限制在道德层面可能难以自圆其说。我们建议在人类生殖克隆成功尝试之前,利用这段时间制定政策和建立机构,以便能基于充分的论据、连贯的道德原则以及广泛的公众咨询,就其合法应用提供明确的指导方针。

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