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上肢深静脉血栓形成:10例研究

[Deep venous thrombosis of the upper extremity: a study of 10 cases].

作者信息

del Arco Galán C, Aguilar R, Suárez Fernández C

机构信息

Servicio de Medicina Interna-Infecciosas, Hospital de la Princesa, Universidad Autónoma, Madrid.

出版信息

Med Clin (Barc). 1991 May 25;96(20):769-71.

PMID:1875763
Abstract

BACKGROUND

Deep venous thrombosis (DVT) of upper limbs is less common than in lower limbs, although an increased prevalence has been observed in recent years.

METHODS

The cases of DVT of upper limbs seen in an internal medicine service during a 24 month period were reviewed. Ten episodes out of overall 103 instances of DVT were identified (9.7%). The diagnosis was confirmed by colour echo-Doppler and/or phlebography. Subcutaneous calcium heparin was subcutaneously given at a dose of 2500 IU per 10 kg of body weight every 12 hours for 7 days, associated with oral anticoagulants given for a variable period in each case.

RESULTS

The predisposing factors were: strenuous physical exercise (2 cases), oral contraceptives (2 cases), C-protein deficiency (1 case), parenteral drug abuse (PDA) (1 case), mediastinal mass (1 case), indwelling catheter (1 case) and absence of an apparent factor (2 cases). The colour echo-Doppler diagnosis was definitive in all cases where the study was carried out (8/10). The response to therapy was favourable in all cases. No case of pulmonary thromboembolism was found and post-phlebitic sequelae did not develop in the patients who could be followed up (6/10).

CONCLUSIONS

The prevalence of deep venous thrombosis of upper limbs is increasing in recent years. The introduction of colour echo-Doppler is a very helpful noninvasive diagnostic procedure. Subcutaneous calcium heparin at the reported dose is a good therapeutic approach.

摘要

背景

上肢深静脉血栓形成(DVT)比下肢少见,尽管近年来其患病率有所上升。

方法

回顾了内科在24个月期间诊治的上肢DVT病例。在总共103例DVT病例中确诊10例(9.7%)。诊断通过彩色多普勒超声和/或静脉造影得以证实。皮下注射钙肝素,剂量为每10千克体重2500国际单位,每12小时一次,共7天,同时根据具体情况给予不同疗程的口服抗凝剂。

结果

诱发因素包括:剧烈体育锻炼(2例)、口服避孕药(2例)、C蛋白缺乏(1例)、静脉药物滥用(1例)、纵隔肿物(1例)、留置导管(1例)以及无明显诱因(2例)。在所有进行彩色多普勒超声检查的病例中(8/10),该检查均能明确诊断。所有病例对治疗反应良好。未发现肺血栓栓塞病例,在可进行随访的患者中(6/10)未出现血栓形成后综合征。

结论

近年来上肢深静脉血栓形成的患病率呈上升趋势。彩色多普勒超声是一种非常有用的无创诊断方法。所报道剂量的皮下注射钙肝素是一种良好的治疗方法。

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Med Clin (Barc). 1991 May 25;96(20):769-71.
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