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秀丽隐杆线虫fog-2突变体中基因转换导致的性别转变

Sex change by gene conversion in a Caenorhabditis elegans fog-2 mutant.

作者信息

Katju Vaishali, LaBeau Elisa M, Lipinski Kendra J, Bergthorsson Ulfar

机构信息

Department of Biology, University of New Mexico, Albuquerque, New Mexico 87131, USA.

出版信息

Genetics. 2008 Sep;180(1):669-72. doi: 10.1534/genetics.108.090035. Epub 2008 Aug 30.

Abstract

Caenorhabditis elegans primarily reproduces as a hermaphrodite. Independent gene conversion events in mutant obligately outcrossing populations of C. elegans [fog-2(lf)] spontaneously repaired the loss-of-function mutation in the fog-2 locus, thereby reestablishing hermaphroditism as the primary means of reproduction for the populations.

摘要

秀丽隐杆线虫主要以雌雄同体的方式进行繁殖。在秀丽隐杆线虫的突变强制杂交群体[fog-2(lf)]中,独立的基因转换事件自发修复了fog-2基因座中的功能丧失突变,从而重新确立雌雄同体为这些群体的主要繁殖方式。

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