Wild Jennifer, Gur Ruben C
King's College London, Department of Psychology, London SE5 8AF, UK.
Br J Psychiatry. 2008 Sep;193(3):254-5. doi: 10.1192/bjp.bp.107.045922.
Post-traumatic stress disorder (PTSD) is often associated with verbal memory deficits, which could influence treatment outcome. We assessed neuropsychological functioning in individuals with PTSD and their response to cognitive-behavioural therapy (CBT). Treatment non-responders had significantly poorer performance on measures of verbal memory compared with responders and demonstrated narrative encoding deficits. Differences were not explained by IQ, performance on tasks of attention, initial PTSD severity, depression, time since trauma, or alcohol/substance misuse. Verbal memory deficits seem to diminish the effectiveness of CBT and should be considered in its implementation.
创伤后应激障碍（PTSD）常与言语记忆缺陷相关，这可能会影响治疗效果。我们评估了PTSD患者的神经心理功能及其对认知行为疗法（CBT）的反应。与有反应者相比，无反应者在言语记忆测量方面的表现明显更差，且存在叙事编码缺陷。智商、注意力任务表现、初始PTSD严重程度、抑郁、创伤后的时间或酒精/物质滥用等因素并不能解释这些差异。言语记忆缺陷似乎会降低CBT的有效性，在实施CBT时应予以考虑。
