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从一种新的断层扫描大鼠模型计算出的光子和电子吸收分数。

Photon and electron absorbed fractions calculated from a new tomographic rat model.

作者信息

Peixoto P H R, Vieira J W, Yoriyaz H, Lima F R A

机构信息

Departamento de Energia Nuclear, Universidade Federal de Pernambuco, Av. Prof. Luiz Freire 1000, Cidade Universitária, CEP 50740-540, Recife, PE, Brazil.

出版信息

Phys Med Biol. 2008 Oct 7;53(19):5343-55. doi: 10.1088/0031-9155/53/19/005. Epub 2008 Aug 29.

Abstract

This paper describes the development of a tomographic model of a rat developed using CT images of an adult male Wistar rat for radiation transport studies. It also presents calculations of absorbed fractions (AFs) under internal photon and electron sources using this rat model and the Monte Carlo code MCNP. All data related to the developed phantom were made available for the scientific community as well as the MCNP inputs prepared for AF calculations in that phantom and also all estimated AF values, which could be used to obtain absorbed dose estimates--following the MIRD methodology--in rats similar in size to the presently developed model. Comparison between the rat model developed in this study and that published by Stabin et al (2006 J. Nucl. Med. 47 655) for a 248 g Sprague-Dawley rat, as well as between the estimated AF values for both models, has been presented.

摘要

本文描述了一种使用成年雄性Wistar大鼠的CT图像开发的大鼠断层模型的进展,用于辐射传输研究。它还展示了使用该大鼠模型和蒙特卡罗代码MCNP对内部光子和电子源下的吸收分数(AFs)的计算。与所开发的体模相关的所有数据都提供给了科学界,以及为该体模中的AF计算准备的MCNP输入数据,还有所有估计的AF值,这些值可用于按照MIRD方法在与当前开发模型大小相似的大鼠中获得吸收剂量估计值。本文还展示了本研究中开发的大鼠模型与Stabin等人(2006年,《核医学杂志》47卷,655页)发表的针对248 g斯普拉格-道利大鼠的模型之间的比较,以及两个模型的估计AF值之间的比较。

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