da Silva Paulo Cesar, de Almeida Patrícia Del Vigna, Machado Maria Angela Naval, de Lima Antônio Adilson Soares, Grégio Ana Maria Trindade, Trevilatto Paula Cristina, Azevedo-Alanis Luciana Reis
Department of Stomatology, School of Dentistry, Pontifícia Universidade Católica do Paraná.
Med Oral Patol Oral Cir Bucal. 2008 Sep 1;13(9):E559-62.
Celiac disease is a chronic intestinal disease caused by intolerance to gluten associated with poor digestion and absorption of the majority of nutrients and vitamins, which may affect both developing dentition and oral mucosa. The aim of this study is to make a brief review of the literature about celiac disease and to report on a clinical case, showing the impact it may have on the general and oral health. A 39-year-old woman reported the presence of diarrhea, nauseas, flatulence, colic, difficulty with falling asleep, lack of appetite and loose of 18 Kg in the last two years. She also noted the appearance of symptomatic lesions in the mouth. These lesions had a mean duration of a month and occurred in any region of the oral mucosa, particularly on the tongue. Multiples ulcerations were found in the sublingual caruncula region, at the vestibular fornix and at the lingual apex. Topical treatment was instituted for the oral lesions with immediately relief of the symptoms. The diagnosis of celiac disease was established by means of medical clinical exam, biopsy of the small intestine, and by the presence of specific antibodies in the blood. The patient has been instructed to follow a gluten-free diet. Multiprofessional action with the involvement of a gastroenterologist and other health professionals, such as dentists, is important for diagnosing the disease and guiding the patient with celiac disease to achieve a good quality of life.
乳糜泻是一种慢性肠道疾病，由对麸质不耐受引起，伴有大多数营养素和维生素的消化吸收不良，可能影响正在发育的牙列和口腔黏膜。本研究的目的是对有关乳糜泻的文献进行简要综述，并报告一例临床病例，展示其对全身健康和口腔健康可能产生的影响。一名39岁女性报告称，在过去两年中出现腹泻、恶心、肠胃胀气、绞痛、入睡困难、食欲不振，体重减轻了18公斤。她还注意到口腔中出现了有症状的病变。这些病变平均持续一个月，发生在口腔黏膜的任何区域，尤其是舌部。在舌下肉阜区域、前庭穹窿和舌尖发现了多处溃疡。对口腔病变进行了局部治疗，症状立即得到缓解。通过医学临床检查、小肠活检以及血液中特定抗体的存在确诊为乳糜泻。已指导该患者遵循无麸质饮食。胃肠病学家和其他健康专业人员（如牙医）参与的多专业行动对于诊断该疾病以及指导乳糜泻患者获得良好生活质量非常重要。
