Husein Omar F, Collins Meredith, Kang D Richard
Department of Otolaryngology, Columbus Children's Hospital and the Ohio State University Medical Center, Columbus, OH, USA.
Eur J Pediatr. 2008 Dec;167(12):1351-5. doi: 10.1007/s00431-008-0810-2. Epub 2008 Aug 30.
Neuroglial heterotopias are rare congenital masses that are thought to represent encephaloceles that become sequestered on the extracranial side of the skull base. Although most often adjacent to bony skull base defects, they lack communication to the subarachnoid space. They contain mature neuroglial tissue and specialized central nervous system elements, such as a functioning choroid plexus. A case is presented of neonatal airway obstruction due to neuroglial heterotopia in the nasopharynx. The patient's clinical course and treatment are discussed, along with their radiology and histology. The relevant scientific literature is reviewed.
神经胶质异位是一种罕见的先天性肿块,被认为是脑膨出在颅底颅外侧面被隔离形成的。虽然它们大多紧邻颅骨基底缺损处,但与蛛网膜下腔并无连通。它们包含成熟的神经胶质组织和专门的中枢神经系统成分,如功能正常的脉络丛。本文介绍了一例因鼻咽部神经胶质异位导致新生儿气道阻塞的病例。讨论了患者的临床病程和治疗情况,以及相关的放射学和组织学表现。并对相关科学文献进行了综述。