Machi Hajime, Karata Hiroki, Yamane Yusuke, Fukuoka Junya, Funakoshi Yasutomo, Moriuchi Hiroyuki
Department of Pediatrics, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, Japan.
Department of Pathology, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, Japan.
Case Rep Otolaryngol. 2017;2017:2413035. doi: 10.1155/2017/2413035. Epub 2017 Sep 20.
Glial choristoma is considered to be a type of brain heterotopia consisting of ectopic central nervous tissue. We herein report a neonate with glial choristoma of the tongue who developed respiratory distress due to airway obstruction. A male neonate presented with respiratory distress due to a soft mass on the midline region of the dorsal tongue base at birth. He was intubated using a flexible fiberoptic nasopharyngoscope. MRI showed a well-circumscribed mass measuring 25 × 23 × 27 mm in size in the same region. A histologic examination confirmed a pathological diagnosis of glial choristoma. He underwent tracheotomy at 22 days of age, and a subtotal resection of the tumor was performed at five months of age. The clinical behavior of oral glial choristoma varies depending on the age at onset as well as the location and size of the mass. The small size of the organ and the narrow operating field hamper the surgical approach in neonates. The optimal therapeutic strategy for neonatal cases of glial choristoma should thus be determined based on the condition of each individual patient.
胶质迷离瘤被认为是一种由异位中枢神经组织构成的脑异位症。我们在此报告一例患有舌部胶质迷离瘤的新生儿,该患儿因气道阻塞出现呼吸窘迫。一名男性新生儿出生时因舌背基底部中线区域的柔软肿物而出现呼吸窘迫。使用可弯曲纤维光学鼻咽喉镜对其进行了插管。MRI显示在同一区域有一个边界清晰的肿物,大小为25×23×27毫米。组织学检查证实了胶质迷离瘤的病理诊断。他在22日龄时接受了气管切开术,并在5月龄时进行了肿瘤次全切除术。口腔胶质迷离瘤的临床行为因发病年龄以及肿物的位置和大小而异。器官体积小和手术视野狭窄妨碍了新生儿的手术入路。因此,应根据每个患儿的具体情况确定新生儿胶质迷离瘤病例的最佳治疗策略。