阻塞性睡眠呼吸暂停：心血管疾病新视角：第二部分：阻塞性睡眠呼吸暂停相关心血管疾病概述。
OSA: the new cardiovascular disease: part II: Overview of cardiovascular diseases associated with obstructive sleep apnea.
机构信息
Division of Pulmonary, Critical Care, and Sleep Medicine, Ohio State University, Columbus, OH, USA.
出版信息
Heart Fail Rev. 2009 Sep;14(3):155-64. doi: 10.1007/s10741-008-9101-2. Epub 2008 Aug 29.
Abstract
Obstructive sleep apnea (OSA), present in 5-15% of adults, is strongly associated with the incidence and poor outcome of hypertension, coronary artery disease, arrhythmia, heart failure, and stroke. Treatment of OSA completely reverses its cardiovascular consequences. In this review, we discuss the clinical evidence for the strong association between OSA and cardiovascular disease and present an argument for approaching OSA as a cardiovascular disease. We particularly focus on the causative relationship between OSA and hypertension, and on the increasingly recognized relationship between OSA and heart failure.
摘要
阻塞性睡眠呼吸暂停（OSA）在 5-15%的成年人中存在，与高血压、冠状动脉疾病、心律失常、心力衰竭和中风的发生和不良预后密切相关。OSA 的治疗可完全逆转其心血管后果。在这篇综述中，我们讨论了 OSA 与心血管疾病之间的强关联的临床证据，并提出了将 OSA 视为一种心血管疾病的观点。我们特别关注 OSA 与高血压之间的因果关系，以及越来越被认识到的 OSA 与心力衰竭之间的关系。
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