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急性胃肠炎患儿临床脱水量表的验证

Validation of the clinical dehydration scale for children with acute gastroenteritis.

作者信息

Goldman Ran D, Friedman Jeremy N, Parkin Patricia C

机构信息

Division of Pediatric Emergency Medicine, BC Children's Hospital, 4480 Oak St, Vancouver, BC V6H 3V4, Canada.

出版信息

Pediatrics. 2008 Sep;122(3):545-9. doi: 10.1542/peds.2007-3141.

Abstract

OBJECTIVE

We previously created a clinical dehydration scale. Our objective was to validate the clinical dehydration scale with a new cohort of patients with acute gastroenteritis who were assessed in a tertiary emergency department in a developed country.

METHODS

A prospective observational study was performed in an emergency department at a large pediatric tertiary center in Canada. Children 1 month to 5 years of age with symptoms of acute gastroenteritis who were assessed in the emergency department were enrolled consecutively during a 4-month period. The main outcome measures were length of stay, proportion of children receiving intravenous fluid rehydration, and proportions of children with abnormal serum pH values or bicarbonate levels.

RESULTS

A total of 205 children were enrolled, with a mean age of 22.4 +/- 14.9 months; 103 (50%) were male. The distribution of severity categories was as follows: no dehydration (score of 0), n = 117 (57%); some dehydration (score of 1-4), n = 83 (41%); moderate/severe dehydration (score of 5-8), n = 5 (2%). The 3 dehydration categories were significantly different with respect to the validation hypotheses (length of stay, mean +/- SD: none, 245 +/- 181 minutes; some, 397 +/- 302 minutes; moderate/severe, 501 +/- 389 minutes; treatment with intravenous fluids: none, n =17, 15%; some, n = 41, 49%; moderate/severe, n = 4, 80%; number of vomiting episodes in the 7 days before the emergency department visit: none, 8.4 +/- 7.7 episodes; some, 13 +/- 10.7 episodes; moderate/severe, 30.2 +/- 14.8 episodes).

CONCLUSION

The clinical dehydration scale and the 3 severity categories were valid for a prospectively enrolled cohort of patients who were assessed in our tertiary emergency department. The scoring system was valuable in predicting a longer length of stay and the need for intravenous fluid rehydration for children with symptoms of acute gastroenteritis.

摘要

目的

我们之前创建了一种临床脱水量表。我们的目的是在一个发达国家的三级急诊科对一组新的急性胃肠炎患者中验证该临床脱水量表。

方法

在加拿大一家大型儿科三级中心的急诊科进行了一项前瞻性观察研究。在4个月期间,连续纳入在急诊科接受评估的1个月至5岁有急性胃肠炎症状的儿童。主要结局指标包括住院时间、接受静脉补液的儿童比例以及血清pH值或碳酸氢盐水平异常的儿童比例。

结果

共纳入205名儿童,平均年龄为22.4±14.9个月;103名(50%)为男性。严重程度分类分布如下:无脱水(评分为0),n = 117名(57%);轻度脱水(评分为1 - 4),n = 83名(41%);中度/重度脱水(评分为5 - 8),n = 5名(2%)。这3种脱水类别在验证假设方面存在显著差异(住院时间,均值±标准差:无脱水,245±181分钟;轻度脱水,397±302分钟;中度/重度脱水,501±389分钟;静脉补液治疗:无脱水,n = 17名,15%;轻度脱水,n = 41名,49%;中度/重度脱水,n = 4名,80%;急诊科就诊前7天呕吐发作次数:无脱水,8.4±7.7次;轻度脱水,13±10.7次;中度/重度脱水,30.2±14.8次)。

结论

该临床脱水量表及3种严重程度分类对于在我们三级急诊科前瞻性纳入的患者队列是有效的。该评分系统对于预测急性胃肠炎症状儿童更长的住院时间及静脉补液需求具有重要价值。

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