Fischer R L, Kuhlman K A, Depp R, Wapner R J
Department of Obstetrics and Gynecology, Jefferson Medical College, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
Obstet Gynecol. 1991 Sep;78(3 Pt 1):363-8.
To assess the correlation between Doppler velocimetry and perinatal outcome in the postdates pregnancy, 75 women who were at least 41 weeks' gestation were evaluated twice weekly until delivery. Evaluation included Doppler velocimetry of the umbilical and uterine-arcuate arteries, as well as nonstress testing and amniotic fluid volume estimation. The mean umbilical artery systolic-diastolic ratio (S/D) was significantly higher in the pregnancies with subsequent abnormal perinatal outcomes than in those with normal outcomes (2.42 versus 2.19; P = .03). Using a receiver operating characteristic curve, an abnormal umbilical artery S/D was defined as 2.40 or greater. Using this value, sensitivity was 57.1% and specificity was 77.8%. Our study suggests that an umbilical artery S/D of 2.40, rather than the more traditionally accepted cutoff of 3.0, may be a useful threshold to identify those postdates pregnancies at high risk for abnormal perinatal outcome.
为评估过期妊娠中多普勒测速与围产期结局之间的相关性,对75名妊娠至少41周的女性每周进行两次评估,直至分娩。评估内容包括脐动脉和子宫弓状动脉的多普勒测速、无应激试验及羊水容量估计。随后出现围产期异常结局的妊娠中,脐动脉收缩期与舒张期比值(S/D)的均值显著高于结局正常的妊娠(分别为2.42和2.19;P = 0.03)。利用受试者工作特征曲线,将异常脐动脉S/D定义为2.40及以上。采用该值时,敏感性为57.1%,特异性为77.8%。我们的研究表明,脐动脉S/D为2.40,而非传统接受的3.0,可能是识别那些有围产期异常结局高风险的过期妊娠的有用阈值。