金属触发的胶原蛋白肽纤维径向自组装。

Metal-triggered radial self-assembly of collagen peptide fibers.

作者信息

Przybyla David E, Chmielewski Jean

机构信息

Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, USA.

出版信息

J Am Chem Soc. 2008 Sep 24;130(38):12610-1. doi: 10.1021/ja804942w. Epub 2008 Sep 3.

DOI:10.1021/ja804942w

PMID:18763780

Abstract

A metal-triggered self-assembling collagen peptide was designed and synthesized to generate fibers through a radial growth mechanism. The assembly of the fibers was made possible through the placement of a bipyridine ligands within the center of the triple helix and was triggered by the addition of Fe(II).

摘要

设计并合成了一种金属触发的自组装胶原蛋白肽，以通过径向生长机制生成纤维。通过在三螺旋中心放置联吡啶配体使纤维的组装成为可能，并通过添加Fe(II)触发。