Koinberg Ingalill, Engholm G-B, Genell A, Holmberg L
Department of Research, Varberg Hospital, Varberg and Kristianstad University, Kristianstad, Sweden.
Acta Oncol. 2009;48(1):99-104. doi: 10.1080/02841860802314712.
Breast cancer follow-up programmes consume large resources and despite the indications that several alternative approaches could be used effectively, there is no coherent discussion about costs and/or cost-effectiveness of follow-up programmes.
In a prospective trial there were 264 breast cancer patients, stage I and II, randomised to two different follow-up programmes- PG (physician group) and NG (nurse group). The trial period was 5 years. The women in the two intervention groups did not differ in anxiety and depression, their satisfaction with care, their experienced accessibility to the medical centre or their medical outcome as measured by recurrence or death. The analyses were done from different lists representing costs at three hospitals in Sweden according to the principles of a cost minimization study.
The cost per person year of follow-up differed between the groups, with 630 euro per person year in PG compared to 495 euro per person year in NG. Thus, specialist nurse intervention with check-ups on demand was 20% less expensive than routine follow-up visits to the physician. The main difference in cost between the groups was explained by the numbers of visits to the physician in the respective study arms. There were 21% more primary contacts in PG than NG.
The difference in cost per year and patient by study arm is modest, but transforms to nearly 900 euro per patient and 5-year period, offering a substantial opportunity for reallocating resources since breast cancer is the most prevalent tumour worldwide.
乳腺癌随访计划耗费大量资源,尽管有迹象表明可以有效采用几种替代方法,但对于随访计划的成本和/或成本效益却没有连贯的讨论。
在一项前瞻性试验中,有264例I期和II期乳腺癌患者,被随机分配到两个不同的随访计划组——PG(医生组)和NG(护士组)。试验期为5年。两个干预组的女性在焦虑和抑郁程度、对护理的满意度、就医中心的可及性体验或通过复发或死亡衡量的医疗结局方面并无差异。根据成本最小化研究的原则,分析是根据瑞典三家医院不同列表中的成本数据进行的。
两组的人均随访年成本有所不同,PG组为每人每年630欧元,而NG组为每人每年495欧元。因此,按需进行检查的专科护士干预比常规的医生随访便宜20%。两组成本的主要差异在于各自研究组中看医生的次数。PG组的初次接触次数比NG组多21%。
按研究组划分,每年和每位患者的成本差异不大,但在5年期间每位患者接近900欧元,鉴于乳腺癌是全球最常见的肿瘤,这为重新分配资源提供了很大机会。