Santa Ursula Tolosa J A, Criado A, García del Valle S, Pensado A, Barbolla L, Carmona Aurioles J A
Servicio de Anestesiología y Reanimación, Clínica Puerta de Hierro, Madrid.
Rev Esp Anestesiol Reanim. 1991 Mar-Apr;38(2):94-7.
The changes in leukocyte overall and differential counts during anesthesia and surgery were evaluated in 24 patients scheduled for cardiac surgery with cardiopulmonary bypass. All the end of cardiopulmonary bypass a marked and sustained leukocytosis was found (10.2 and 11.1 x 10(9).l-1), which was significantly different from baseline values (6.7 x 10(9).l-1), the values previous to cardiopulmonary bypass (6.2 and 6.4 x 10(9).l-1, and the values 30 minutes after it (5.3 x 10(9).l-1). In the differential count there were significant increases in neutrophils, associated with band and immature forms, corresponding with significant reductions in lymphocytes. There was no significant association of leukocyte variability during and after cardiopulmonary bypass and the perfusion time, the type of oxygenator or the need for intraoperative transfusion. All the reported changes tended to become normal during the first postoperative days.
对24例计划进行体外循环心脏手术的患者，评估了麻醉和手术期间白细胞总数及分类计数的变化。在体外循环结束时，发现明显且持续的白细胞增多（分别为10.2和11.1×10⁹/L），这与基线值（6.7×10⁹/L）、体外循环前的值（6.2和6.4×10⁹/L）以及体外循环后30分钟的值（5.3×10⁹/L）有显著差异。在分类计数中，中性粒细胞显著增加，伴有杆状核和未成熟形式，同时淋巴细胞显著减少。体外循环期间及之后白细胞变异性与灌注时间、氧合器类型或术中输血需求之间无显著关联。所有报告的变化在术后头几天往往趋于正常。
