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经单鼻孔联合内镜与显微镜治疗小儿垂体区肿瘤:技术说明及病例图示

Combined endoscopic and microscopic management of pediatric pituitary region tumors through one nostril: technical note with case illustrations.

作者信息

Frazier James L, Chaichana Kaisorn, Jallo George I, Quiñones-Hinojosa Alfredo

机构信息

Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD 21231, USA.

出版信息

Childs Nerv Syst. 2008 Dec;24(12):1469-78. doi: 10.1007/s00381-008-0710-9. Epub 2008 Sep 4.

Abstract

OBJECTIVE

Sellar and parasellar lesions in the pediatric population have traditionally been approached through either a transsphenoidal hypophysectomy or craniotomy or a combination of the two, with the surgical approach being dictated by the anatomical location and extent of the pathology. The introduction and evolution of the endonasal endoscopic technique has provided a minimally invasive method alone or in combination with the operative microscope for removal of these lesions in the pediatric population. The authors have implemented in their practice the use of endonasal endoscopic-assisted microsurgery in the pediatric population harboring sellar and/or lesions extending to the suprasellar space and report our experience in nine patients.

MATERIALS AND METHODS

Five craniopharyngiomas, one Rathke's cleft cyst, and two pituitary tumors were treated via endonasal endoscopic-assisted microsurgery. Histopathologic examination revealed lymphocytic hypophysitis in one patient with an enhancing lesion in the pituitary stalk. The approach utilized by the authors is performed through one nostril without any resection of the nasal turbinates or nasal septum. The middle turbinate is displaced laterally, while the nasal septum is moved medially.

CONCLUSION

Gross total, near-total, and subtotal resections and a diagnostic biopsy were obtained in six, one, one, and one patients, respectively. The authors were able to safely perform this procedure in nine pediatric patients, and the lack of turbinate or septum resection minimized postoperative discomfort.

摘要

目的

传统上,儿童鞍区及鞍旁病变的治疗方法是经蝶窦垂体切除术、开颅手术或两者结合,手术方式取决于病变的解剖位置和范围。鼻内镜技术的引入和发展为儿童患者单独或联合手术显微镜切除这些病变提供了一种微创方法。作者在其临床实践中对患有鞍区和/或延伸至鞍上间隙病变的儿童患者采用了鼻内镜辅助显微手术,并报告了9例患者的经验。

材料与方法

通过鼻内镜辅助显微手术治疗了5例颅咽管瘤、1例拉克氏囊肿和2例垂体瘤。组织病理学检查显示1例患者为淋巴细胞性垂体炎,垂体柄有强化病变。作者采用的手术入路是通过一个鼻孔进行,不切除鼻甲或鼻中隔。中鼻甲向外侧移位,鼻中隔向内侧移动。

结论

分别有6例、1例、1例和1例患者实现了全切除、近全切除、次全切除和诊断性活检。作者能够在9例儿童患者中安全地进行该手术,并且未切除鼻甲或鼻中隔使术后不适降至最低。

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