Quaranta Alessandro, Piattelli Adriano, Scarano Antonio, Quaranta Manlio, Pompa Giorgio, Iezzi Giovanna
Dental School, La Sapienza University of Rome, Rome, Italy.
J Periodontol. 2008 Sep;79(9):1697-703. doi: 10.1902/jop.2008.070631.
Immediate loading of dental implants is a successful treatment concept. The importance of healthy peri-implant soft tissues for the long-term success of dental implants has been widely recognized. The aim of this study was to evaluate the peri-implant soft tissues around immediately loaded and submerged implants in monkeys.
A total of 48 implants were inserted in six Macaca fascicularis monkeys. For 24 implants (test implants), the prosthetic abutments were inserted immediately, and a custom-made metal superstructure was cemented after 3 days; the other 24 implants were left unloaded (control implants). Block sections of bone segments containing the implants were retrieved 9 months after surgical placement. A histomorphometric measurement of sulcular epithelium (SE), junctional epithelium (JE), and connective tissue (CT) contact percentage of the soft tissues around test and control implants was carried out.
In some specimens, the peri-implant epithelium was very similar to a pocket epithelium, whereas in others it was possible to observe an SE and a long junctional-like epithelium with a moderate amount of inflammatory cells. The supracrestal peri-implant CT was dense and organized in collagen fibrous bundles in an annular pattern around the implant. No statistically significant differences were present in the dimensions of SE, JE, and CT in test and control implants (P >0.05).
Immediate loading did not produce changes in the dimensions of the peri-implant soft tissues.
牙种植体即刻负重是一种成功的治疗理念。健康的种植体周围软组织对牙种植体长期成功的重要性已得到广泛认可。本研究的目的是评估猕猴中即刻负重种植体和潜入式种植体周围的种植体周围软组织。
在6只食蟹猴中总共植入48枚种植体。对于24枚种植体（试验种植体），即刻植入修复基台，3天后粘结定制的金属上部结构；另外24枚种植体不进行负重（对照种植体）。手术植入9个月后取出包含种植体的骨段的块状切片。对试验种植体和对照种植体周围软组织的龈沟上皮（SE）、结合上皮（JE）和结缔组织（CT）接触百分比进行组织形态计量学测量。
在一些标本中，种植体周围上皮与袋状上皮非常相似，而在其他标本中，可以观察到SE和具有中等数量炎性细胞的长结合样上皮。种植体周围龈上CT致密，并以环形模式围绕种植体组织成胶原纤维束。试验种植体和对照种植体的SE、JE和CT尺寸无统计学显著差异（P>0.05）。
即刻负重未引起种植体周围软组织尺寸的改变。
