Crosby Richard A, Diclemente Ralph J, Wingood Gina M, Salazar Laura F, Lang Delia, Rose Eve, McDermott-Sales Jessica
College of Public Health, University of Kentucky, 121 Washington Avenue, Lexington, KY 40506, USA.
Sex Health. 2008 Sep;5(3):285-9. doi: 10.1071/sh07098.
The co-occurrence of a behaviour (being intoxicated on alcohol/drugs during sex) with a disease outcome [laboratory-confirmed sexually transmissible infection (STI) prevalence] among young African American women and their male sex partners was studied.
A cross-sectional study was conducted. Recruitment and data collection occurred in three clinics located in a metropolitan city of the Southern USA. A total of 715 African American adolescent females (15-21 years old) were enrolled (82% participation rate). The primary outcome measure was the analysis of self-collected vaginal swabs using nucleic acid amplification assays for Trichomonas vaginalis, Chlamydia trachomatis, and Neisseria gonorrhoeae.
After controlling for age and self-efficacy to negotiate condom use, young women's alcohol/drug use while having sex was not significantly associated with STI prevalence [adjusted odds ratios (AOR) = 1.29, 95% confidence interval (CI) = 0.90-1.83]. However, using the same covariates, the association between male partners' alcohol/drug use and sexually transmitted disease prevalence was significant (AOR = 1.44, 95% CI = 1.03-2.02). Young women reporting that their sex partners had been drunk or high while having sex (at least once in the past 60 days) were approximately 1.4 times more likely to test positive for at least one of the three assessed STIs.
Young African American women reporting a male sex partner had been intoxicated during sex were significantly more likely to have an STI. The nature of this phenomenon could be a consequence of women's selection of risky partners and lack of condom use possibly stemming from their intoxication or their partners' intoxication.
研究了年轻非裔美国女性及其男性性伴侣中一种行为（性行为期间酒精/药物中毒）与疾病结局[实验室确诊的性传播感染（STI）患病率]的共现情况。
进行了一项横断面研究。招募和数据收集在美国南部一个大城市的三家诊所进行。共纳入715名非裔美国青少年女性（15 - 21岁）（参与率82%）。主要结局指标是使用核酸扩增检测法对自行采集的阴道拭子进行分析，检测阴道毛滴虫、沙眼衣原体和淋病奈瑟菌。
在控制年龄和协商使用避孕套的自我效能感后，年轻女性性行为时的酒精/药物使用与STI患病率无显著关联[调整优势比（AOR）= 1.29，95%置信区间（CI）= 0.90 - 1.83]。然而，使用相同的协变量，男性伴侣的酒精/药物使用与性传播疾病患病率之间的关联显著（AOR = 1.44，95% CI = 1.03 - 2.02）。报告其性伴侣在性行为时喝醉或吸毒（过去60天内至少一次）的年轻女性，感染三种评估的STI中至少一种的可能性大约高1.4倍。
报告男性性伴侣在性行为时醉酒的年轻非裔美国女性感染STI的可能性显著更高。这种现象的本质可能是女性选择高危伴侣以及可能因自身或伴侣醉酒而未使用避孕套的结果。
