Suppr超能文献

经食管超声心动图评估外科左心耳封堵术的成功率

Success of surgical left atrial appendage closure: assessment by transesophageal echocardiography.

作者信息

Kanderian Anne S, Gillinov A Marc, Pettersson Gosta B, Blackstone Eugene, Klein Allan L

机构信息

Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA.

出版信息

J Am Coll Cardiol. 2008 Sep 9;52(11):924-9. doi: 10.1016/j.jacc.2008.03.067.

Abstract

OBJECTIVES

We sought to determine which surgical technique of left atrial appendage (LAA) closure is most successful by assessing them with transesophageal echocardiography (TEE).

BACKGROUND

Atrial fibrillation is a risk factor for stroke, with 90% of clots occurring in the LAA. Several surgical techniques of LAA closure are used to theoretically reduce the stroke risk, with varying success rates.

METHODS

A total of 137 of 2,546 patients who underwent surgical LAA closure from 1993 to 2004 had a TEE after surgery. Techniques consisted of either excision or exclusion by sutures or stapling. The TEE measurements included color Doppler flow in the LAA and interrogation for thrombus. Patent LAA, remnant LAA (residual stump >1 cm), or excluded LAA with persistent flow into the LAA were identified as unsuccessful closure.

RESULTS

Of the 137 patients, 52 (38%) underwent excision and 85 (62%) underwent exclusion (73 suture and 12 stapler). Only 55 of 137 (40%) of closures were successful. Successful LAA closure occurred more often with excision (73%) than suture exclusion (23%) and stapler exclusion (0%) (p < 0.001). We found LAA thrombus to be present in 28 of 68 patients (41%) with unsuccessful LAA exclusion versus none with excision. At time of TEE, 6 patients with successful LAA closure (11%) and 12 with unsuccessful closure (15%) had evidence of stroke/transient ischemic attack (p = 0.61).

CONCLUSIONS

There is a high occurrence of unsuccessful surgical LAA closure. Of the various techniques, excision appears to be the most successful.

摘要

目的

我们试图通过经食管超声心动图(TEE)评估,确定哪种左心耳(LAA)闭合手术技术最为成功。

背景

心房颤动是中风的危险因素,90%的血栓形成于左心耳。理论上,几种LAA闭合手术技术可降低中风风险,但成功率各不相同。

方法

1993年至2004年接受LAA闭合手术的2546例患者中,共有137例术后接受了TEE检查。技术包括切除或用缝线或吻合器进行封堵。TEE测量包括LAA内的彩色多普勒血流以及血栓检查。LAA通畅、残余LAA(残余残端>1 cm)或封堵后仍有血流持续进入LAA被视为封堵失败。

结果

137例患者中,52例(38%)接受了切除手术,85例(62%)接受了封堵手术(73例用缝线,12例用吻合器)。137例封堵中仅55例(40%)成功。LAA切除术后成功闭合的发生率(73%)高于缝线封堵(23%)和吻合器封堵(0%)(p<0.001)。我们发现,68例LAA封堵失败的患者中有28例(41%)存在LAA血栓,而切除术后无一例出现。在TEE检查时,LAA闭合成功的6例患者(11%)和闭合失败的12例患者(15%)有中风/短暂性脑缺血发作的证据(p = 0.61)。

结论

LAA手术闭合失败的发生率很高。在各种技术中,切除似乎是最成功的。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验