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1
The association of race, gender, and comorbidity with mortality and function after hip fracture.种族、性别和合并症与髋部骨折后死亡率及功能的关联。
J Gerontol A Biol Sci Med Sci. 2008 Aug;63(8):867-72. doi: 10.1093/gerona/63.8.867.
2
No Major Differences in Recovery After Hip Fracture Between Home-Dwelling Female and Male Patients.居家女性和男性髋部骨折患者术后恢复无显著差异。
Scand J Surg. 2020 Sep;109(3):250-264. doi: 10.1177/1457496919847932. Epub 2019 May 15.
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Delirium is independently associated with poor functional recovery after hip fracture.谵妄与髋部骨折后功能恢复不佳独立相关。
J Am Geriatr Soc. 2000 Jun;48(6):618-24. doi: 10.1111/j.1532-5415.2000.tb04718.x.
4
Less than one-third of hip fracture patients return to their prefracture level of instrumental activities of daily living in a prospective cohort study of 480 patients.在一项对 480 名患者的前瞻性队列研究中,不到三分之一的髋部骨折患者在返回骨折前的日常生活活动工具性活动水平。
Geriatr Gerontol Int. 2018 Aug;18(8):1244-1248. doi: 10.1111/ggi.13471. Epub 2018 Jul 13.
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Physical therapy and mobility 2 and 6 months after hip fracture.髋部骨折后2个月和6个月时的物理治疗与活动能力
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6
Recovery of Walking Ability and Return to Community Living within 60 Days of Hip Fracture Does Not Differ Between Male and Female Survivors.髋部骨折后60天内步行能力的恢复及回归社区生活情况,男性和女性幸存者之间并无差异。
J Am Geriatr Soc. 2015 Aug;63(8):1640-4. doi: 10.1111/jgs.13535. Epub 2015 Jul 22.
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Comorbidity and mortality following hip fracture: a population-based cohort study.髋部骨折后的合并症与死亡率:一项基于人群的队列研究。
Aging Clin Exp Res. 2008 Oct;20(5):412-8. doi: 10.1007/BF03325146.
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Most patients regain prefracture basic mobility after hip fracture surgery in a fast-track programme.在快速康复计划下,大多数患者在髋部骨折手术后恢复到骨折前的基本活动能力。
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Factors associated with changes in mobility and living arrangements in a comprehensive geriatric outpatient assessment after hip fracture.髋部骨折后综合老年门诊评估中与活动能力和生活安排变化相关的因素。
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More than half of hip fracture patients do not regain mobility in the first postoperative year.超过一半的髋部骨折患者在术后第一年无法恢复活动能力。
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Risk factors for and prognosis of postoperative cardiac events in older patients with hip fractures: a retrospective cohort study.老年髋部骨折患者术后心脏事件的危险因素及预后:一项回顾性队列研究。
J Orthop Surg Res. 2025 Aug 12;20(1):764. doi: 10.1186/s13018-025-06175-3.
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Disparity in Access and Poorer Health Status in Non-Majority Populations.少数族裔人群在医疗服务可及性方面的差异及较差的健康状况。
J Pediatr Soc North Am. 2024 Feb 12;5(Suppl 1):594. doi: 10.55275/JPOSNA-2023-594. eCollection 2023 Feb 15.
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Ethnic and racial minority patients are under-represented in US clinical trials for surgical management of hip fractures.在美国髋部骨折手术治疗的临床试验中,少数族裔患者的参与人数不足。
Injury. 2025 Jul;56(7):112413. doi: 10.1016/j.injury.2025.112413. Epub 2025 May 6.
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Racial Disparities in Outpatient Physical Therapy Use After Hip Fracture: A Retrospective Cohort Study.髋部骨折后门诊物理治疗使用的种族差异:一项回顾性队列研究。
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Racial and Ethnic Disparities in Hip Fracture Surgery: A Systematic Review and Meta-Analysis.髋部骨折手术中的种族和族裔差异:一项系统评价和荟萃分析。
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Sex differences in mobility recovery after hip fracture: a time series analysis.髋部骨折后活动能力恢复的性别差异:时间序列分析。
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Preoperative cardiology consultations for geriatric patients with hip fractures rarely provide additional recommendations and are associated with prolonged hospital stays and delayed surgery: a retrospective case control study.老年髋部骨折患者术前心脏科会诊很少能提供额外建议,且与住院时间延长和手术延迟相关:一项回顾性病例对照研究。
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Risk factors associated with 1-year mortality after osteoporotic hip fracture in Hawai'i: higher mortality risk among Native Hawaiians and other Pacific Islanders.夏威夷骨质疏松性髋部骨折后 1 年死亡率的相关风险因素:夏威夷原住民和其他太平洋岛民的死亡率风险更高。
Osteoporos Int. 2024 Nov;35(11):1931-1941. doi: 10.1007/s00198-024-07195-1. Epub 2024 Jul 30.
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Disparities in Osteoporosis Prevention and Care: Understanding Gender, Racial, and Ethnic Dynamics.骨质疏松症预防与护理的差异:理解性别、种族和民族动态
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Pre-operative Anemia and Hyponatremia Increase the Risk of Mortality in Elderly Hip Fractures.术前贫血和低钠血症增加老年髋部骨折患者的死亡风险。
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本文引用的文献

1
Heterogeneity in hip fracture patients: age, functional status, and comorbidity.髋部骨折患者的异质性:年龄、功能状态和合并症。
J Am Geriatr Soc. 2007 Mar;55(3):407-13. doi: 10.1111/j.1532-5415.2007.01078.x.
2
Adjusted mortality after hip fracture: From the cardiovascular health study.髋部骨折后的校正死亡率:来自心血管健康研究。
J Am Geriatr Soc. 2006 Dec;54(12):1885-91. doi: 10.1111/j.1532-5415.2006.00985.x.
3
Predictors of mortality after hip fracture: results from 1-year follow-up.髋部骨折后死亡率的预测因素:1年随访结果
Aging Clin Exp Res. 2006 Oct;18(5):381-7. doi: 10.1007/BF03324834.
4
The influence of cognitive function on outcome after a hip fracture.认知功能对髋部骨折后预后的影响。
J Bone Joint Surg Am. 2006 Oct;88(10):2115-23. doi: 10.2106/JBJS.E.01409.
5
Gender differences in functioning after hip fracture.髋部骨折后功能的性别差异。
J Gerontol A Biol Sci Med Sci. 2006 May;61(5):495-9. doi: 10.1093/gerona/61.5.495.
6
Effect of comorbidities and postoperative complications on mortality after hip fracture in elderly people: prospective observational cohort study.共病和术后并发症对老年髋部骨折患者死亡率的影响:前瞻性观察队列研究
BMJ. 2005 Dec 10;331(7529):1374. doi: 10.1136/bmj.38643.663843.55. Epub 2005 Nov 18.
7
Gender differences in patients with hip fracture: a greater risk of morbidity and mortality in men.髋部骨折患者的性别差异:男性发病和死亡风险更高。
J Orthop Trauma. 2005 Jan;19(1):29-35. doi: 10.1097/00005131-200501000-00006.
8
Factors associated with mortality and functional disability after hip fracture: an inception cohort study.髋部骨折后与死亡率和功能残疾相关的因素:一项队列起始研究。
Osteoporos Int. 2005 Jul;16(7):729-36. doi: 10.1007/s00198-004-1740-0. Epub 2004 Oct 30.
9
Association of timing of surgery for hip fracture and patient outcomes.髋部骨折手术时机与患者预后的关联
JAMA. 2004 Apr 14;291(14):1738-43. doi: 10.1001/jama.291.14.1738.
10
Effect of medical conditions on improvement in self-reported and observed functional performance of elders.医疗状况对老年人自我报告及观察到的功能表现改善的影响。
J Am Geriatr Soc. 2004 Feb;52(2):217-23. doi: 10.1046/j.0002-8614.2004.52057.x.

种族、性别和合并症与髋部骨折后死亡率及功能的关联。

The association of race, gender, and comorbidity with mortality and function after hip fracture.

作者信息

Penrod Joan D, Litke Ann, Hawkes William G, Magaziner Jay, Doucette John T, Koval Kenneth J, Silberzweig Stacey B, Egol Kenneth A, Siu Albert L

机构信息

Geriatric Research, Eeducation, and Clinical Center, James J. Peters VA Medical Center, 130 Kingsbridge Road, Bronx, NY 10468, USA.

出版信息

J Gerontol A Biol Sci Med Sci. 2008 Aug;63(8):867-72. doi: 10.1093/gerona/63.8.867.

DOI:10.1093/gerona/63.8.867
PMID:18772476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3807236/
Abstract

BACKGROUND

Few studies of hip fracture have large enough samples of men, minorities, and persons with specific comorbidities to examine differences in their mortality and functional outcomes. To address this problem, we combined three cohorts of hip fracture patients to produce a sample of 2692 patients followed for 6 months.

METHOD

Data on mortality, mobility, and other activities of daily living (ADLs) were available from all three cohorts. We used multiple regression to examine the association of race, gender, and comorbidity with 6-month survival and function, controlling for prefracture mobility and ADLs, age, fracture type, cohort, and admission year.

RESULTS

The mortality rate at 6 months was 12%: 9% for women and 19% for men. Whites and women were more likely than were nonwhites and men to survive to 6 months, after adjusting for age, comorbidities, and prefracture mobility and function. Whites were more likely than were nonwhites to walk independently or with help at 6 months compared to not walking, after adjusting for age, comorbidities, and prefracture mobility and function. Dementia had a negative impact on survival, mobility, and ADLs at 6 months. The odds of survival to 6 months were significantly lower for people with chronic obstructive pulmonary disease (COPD), congestive heart failure (CHF), and/or cancer. Parkinson's disease and stroke had negative impacts on mobility and ADLs, respectively, among survivors at 6 months.

CONCLUSIONS

The finding of higher mortality and worse mobility for nonwhite patients with hip fractures highlights the need for more research on race/ethnicity disparities in hip fracture care.

摘要

背景

很少有关于髋部骨折的研究拥有足够大的男性、少数族裔以及患有特定合并症患者的样本,以检验他们在死亡率和功能结局方面的差异。为了解决这一问题,我们合并了三个髋部骨折患者队列,形成了一个2692例患者的样本,并对其进行了6个月的随访。

方法

所有三个队列均提供了关于死亡率、活动能力以及其他日常生活活动(ADL)的数据。我们使用多元回归分析来检验种族、性别和合并症与6个月生存率和功能之间的关联,并对骨折前的活动能力和ADL、年龄、骨折类型、队列以及入院年份进行了控制。

结果

6个月时的死亡率为12%:女性为9%,男性为19%。在对年龄、合并症以及骨折前的活动能力和功能进行调整后,白人和女性比非白人和男性更有可能存活至6个月。在对年龄、合并症以及骨折前的活动能力和功能进行调整后,与无法行走相比,白人在6个月时更有可能独立行走或在他人帮助下行走。痴呆对6个月时的生存、活动能力和ADL有负面影响。患有慢性阻塞性肺疾病(COPD)、充血性心力衰竭(CHF)和/或癌症的患者存活至6个月的几率显著较低。帕金森病和中风分别对6个月时幸存者的活动能力和ADL有负面影响。

结论

髋部骨折的非白人患者死亡率较高且活动能力较差这一发现凸显了对髋部骨折护理中种族/族裔差异进行更多研究的必要性。