Nahar B, Hamadani J D, Ahmed T, Tofail F, Rahman A, Huda S N, Grantham-McGregor S M
International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
Eur J Clin Nutr. 2009 Jun;63(6):725-31. doi: 10.1038/ejcn.2008.44. Epub 2008 Sep 3.
BACKGROUND/OBJECTIVES: Young children with severe malnutrition usually have poor mental development. Psychosocial stimulation may reduce their cognitive deficit, but it is not usually provided. The aim of the study was to incorporate stimulation into the routine treatment of severely malnourished children in a nutrition unit and evaluate the impact on their growth and development.
Time-lagged controlled study.
Nutritional Rehabilitation Unit (NRU) in ICDDR,B Dhaka Hospital.
Severely malnourished children, aged 6-24 months, admitted to the NRU were enrolled. All received standard nutritional care. A control group of 43 children was studied initially, followed by an intervention group of 54 children. The intervened mothers and children participated in daily group meetings and individual play sessions for 2 weeks in hospital and were visited at home for 6 months. Children's growth was measured and development assessed using the Bayley Scales of Infant Development.
Twenty-seven children were lost to the study. In the remaining children, both groups had similar developmental scores and anthropometry initially. After 6 months, the intervention group had improved more than the controls did by a mean of 6.9 (P<0.001; 95% CI: 3.9, 10.0) mental and 3.1 (P=0.024; 95% CI: 0.4, 5.7) motor raw scores and a mean of 0.4 (P=0.029; 95% CI: 0.1, 0.8) weight-for-age z scores, controlling for background variables.
Psychosocial stimulation integrated into treatment of severely malnourished children in hospital, followed by home visits for 6 months, was effective in improving children's growth and development and should be an integral part of their treatment.
背景/目的:患有严重营养不良的幼儿通常智力发育较差。心理社会刺激可能会减少他们的认知缺陷,但通常并未提供此类刺激。本研究的目的是将刺激措施纳入营养科对严重营养不良儿童的常规治疗中,并评估其对儿童生长发育的影响。
时间滞后对照研究。
达卡医院国际腹泻病研究中心孟加拉国分院的营养康复科。
纳入入住营养康复科的6至24个月大的严重营养不良儿童。所有儿童均接受标准营养护理。最初对43名儿童组成的对照组进行研究,随后对54名儿童组成的干预组进行研究。接受干预的母亲和儿童在医院参加了为期2周的每日小组会议和个体游戏环节,并在6个月内进行了家访。使用贝利婴儿发育量表测量儿童的生长情况并评估发育状况。
27名儿童退出研究。在其余儿童中,两组最初的发育得分和人体测量指标相似。6个月后,在控制背景变量的情况下,干预组在智力原始得分方面比对照组平均提高了6.9(P<0.001;95%置信区间:3.9,10.0),在运动原始得分方面提高了3.1(P=0.024;95%置信区间:0.4,5.7),在年龄别体重z评分方面平均提高了0.4(P=0.029;95%置信区间:0.1,0.8)。
将心理社会刺激纳入住院严重营养不良儿童的治疗中,并在6个月内进行家访,可有效改善儿童的生长发育,应成为其治疗的一个组成部分。