Drain O, Lenoir T, Dauzac C, Rillardon L, Guigui P
Service de Chirurgie Orthopédique, Assistance Publique-Hôpitaux de Paris, Hôpital Beaujon, Clichy, France.
Rev Chir Orthop Reparatrice Appar Mot. 2008 Sep;94(5):472-80. doi: 10.1016/j.rco.2008.03.031. Epub 2008 May 21.
Experimentally, posterolateral fusion only provides incomplete control of flexion-extension, rotation and lateral inclination forces. The stability deficit increases with increasing height of the anterior intervertebral space, which for some warrants the adjunction of an intersomatic arthrodesis in addition to the posterolateral graft. Few studies have been devoted to the impact of disc height on the outcome of posterolateral fusion. The purpose of this work was to investigate the spinal segment immobilized by the posterolateral fusion: height of the anterior intervertebral space, the clinical and radiographic impact of changes in disc height, and the short- and long-term impact of disc height measured preoperatively on clinical and radiographic outcome.
In order to obtain a homogeneous group of patients, the series was limited to patients undergoing posterolateral arthrodesis for degenerative spondylolisthesis, in combination with radicular release. This was a retrospective analysis of a consecutive series of 66 patients with mean 52 months follow-up (range 3-63 months). A dedicated self-administered questionnaire was used to collect data on pre- and postoperative function, the SF-36 quality of life score, and patient satisfaction. Pre- and postoperative (early, one year, last follow-up) radiographic data were recorded: olisthesic level, disc height, intervertebral angle, intervertebral mobility (angular, anteroposterior), and global measures of sagittal balance (thoracic kyphosis, lumbar lordosis, T9 sagittal tilt, pelvic version, pelvic incidence, sacral slope). SpineView was used for all measures. Univariate analysis searched for correlations between variation in disc height and early postoperative function and quality of fusion at last follow-up. Multivariate analysis was applied to the following preoperative parameters: intervertebral angle, disc height, intervertebral mobility, sagittal balance parameters, use of osteosynthesis or not.
At the olisthesic level, there was a 30% mean decrease in disc height and intervertebral angle. These variations were not correlated with functional outcome or quality of fusion observed at last follow-up. Disc height preoperatively did not affect these variations. The only factor correlated with decreased disc height was T9 sagittal tilt: disc height decreased more when T9 sagittal tilt approached 0 degrees .
In this very restricted context (retrospective study, short arthrodesis for degenerative spondylolisthesis), we were unable to find any evidence supporting the notion that high disc height is an argument which should favor complementary intersomatic arthrodesis in combination with posterolateral fusion. Analysis of the spinal balance in the sagittal plane would probably allow a more pertinent assessment of the specific needs of individual patients.
在实验中,后外侧融合仅能不完全控制屈伸、旋转和侧倾力量。随着椎间隙前部高度增加,稳定性不足加剧,这使得一些人认为除后外侧植骨外还需进行椎间融合术。很少有研究关注椎间盘高度对后外侧融合结果的影响。本研究的目的是调查后外侧融合固定的脊柱节段:椎间隙前部高度、椎间盘高度变化的临床和影像学影响,以及术前测量的椎间盘高度对临床和影像学结果的短期和长期影响。
为获得一组同质患者,该系列仅限于因退行性腰椎滑脱症接受后外侧关节融合术并伴有神经根松解的患者。这是一项对连续66例患者的回顾性分析,平均随访52个月(范围3 - 63个月)。使用一份专门的自填问卷收集术前和术后功能、SF - 36生活质量评分及患者满意度的数据。记录术前和术后(早期、一年、末次随访)的影像学数据:滑脱节段、椎间盘高度、椎间角度、椎间活动度(角度、前后方向)以及矢状面平衡的整体测量值(胸椎后凸、腰椎前凸、T9矢状倾斜、骨盆倾斜度、骨盆入射角、骶骨坡度)。所有测量均使用SpineView。单因素分析寻找椎间盘高度变化与术后早期功能及末次随访时融合质量之间的相关性。多因素分析应用于以下术前参数:椎间角度、椎间盘高度、椎间活动度、矢状面平衡参数、是否使用内固定。
在滑脱节段,椎间盘高度和椎间角度平均下降30%。这些变化与末次随访时观察到的功能结果或融合质量无关。术前椎间盘高度不影响这些变化。与椎间盘高度降低相关的唯一因素是T9矢状倾斜:当T9矢状倾斜接近0度时,椎间盘高度下降更多。
在这个非常有限的背景下(回顾性研究,针对退行性腰椎滑脱症的短节段融合),我们未能找到任何证据支持高椎间盘高度应有利于后外侧融合联合补充性椎间融合术这一观点。矢状面脊柱平衡分析可能会对个体患者的特定需求进行更恰当的评估。