Chitnis Shilpa
Clinical Center for Movement Disorders, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9036, USA.
Neurol Clin. 2008 Aug;26(3 Suppl):S29-44, v-vi. doi: 10.1016/j.ncl.2008.05.005.
Parkinsonism is a syndrome characterized by a combination of cardinal features including resting tremor, bradykinesia, rigidity, and loss of postural reflexes. The most common presentation of parkinsonism is the idiopathic variety first described by James Parkinson in 1817 now known as Parkinson's disease (PD). This article focuses on identifying the different subtypes of PD, with the recognition that treatment approaches may differ depending on the initial presenting feature. It also addresses issues related to the recognition and treatment of nonmotor comorbidities of PD, such as autonomic dysfunction and neuropsychiatric problems including depression and dementia.
帕金森综合征是一种以静止性震颤、运动迟缓、肌强直和姿势反射丧失等主要特征为组合的综合征。帕金森综合征最常见的表现是1817年由詹姆斯·帕金森首次描述的特发性类型，现在称为帕金森病（PD）。本文重点在于识别帕金森病的不同亚型，同时认识到治疗方法可能因最初的表现特征而异。它还讨论了与帕金森病非运动合并症的识别和治疗相关的问题，如自主神经功能障碍以及包括抑郁和痴呆在内的神经精神问题。
