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有过一次心肌梗死愈合的患者运动试验结果为阳性和阴性,且伴有或不伴有运动诱发型心绞痛:基线变量及长期预后分析

Positive and negative exercise test results with and without exercise-induced angina in patients with one healed myocardial infarction: analysis of baseline variables and long-term prognosis.

作者信息

Karnegis J N, Matts J P, Tuna N, Amplatz K

机构信息

University of Nebraska, Omaha.

出版信息

Am Heart J. 1991 Sep;122(3 Pt 1):701-8. doi: 10.1016/0002-8703(91)90514-i.

DOI:10.1016/0002-8703(91)90514-i
PMID:1877445
Abstract

The prognostic implications of exercise test results with and without exercised-induced angina are not completely understood. In the Program On the Surgical Control Of the Hyperlipidemias (POSCH), 838 subjects with hyperlipidemia who had one healed myocardial infarction were studied and followed for 6 to 13 years (mean 8.6). Of the 417 control subjects, 279 had a treadmill exercise test result that was definitely positive or negative. Angina was also induced by exercise in 30% (45/150) and 8% (10/129) of those with a positive and a negative test result, respectively (p less than 0.0001). The data showed no difference between subjects with a positive or a negative test result with or without angina as regards levels of blood lipids, type of myocardial infarction (Q or non-Q wave), left ventricular function, or prognosis as defined by death, atherosclerotic coronary heart disease death, or myocardial infarction.

摘要

运动试验结果伴或不伴运动诱发心绞痛的预后意义尚未完全明确。在“高脂血症外科治疗计划”(POSCH)中,对838例患有高脂血症且有一次陈旧性心肌梗死的受试者进行了研究,并随访6至13年(平均8.6年)。在417例对照受试者中,279例的平板运动试验结果为明确阳性或阴性。运动试验结果为阳性和阴性的受试者中,分别有30%(45/150)和8%(10/129)诱发了心绞痛(p<0.0001)。数据显示,运动试验结果为阳性或阴性且伴有或不伴有心绞痛的受试者在血脂水平、心肌梗死类型(Q波或非Q波)、左心室功能或由死亡、动脉粥样硬化性冠心病死亡或心肌梗死定义的预后方面均无差异。

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