Pérez Tato Berta, Sáez Asunción Cuenca, Fernández Pedro Ruiz
Department of Dermatology, Hospital Clínico San Carlos, Madrid 28040, Spain.
Ann Diagn Pathol. 2008 Oct;12(5):375-7. doi: 10.1016/j.anndiagpath.2007.02.005. Epub 2007 Oct 24.
We report a case of a superficial angiomyxoma with a trichofolliculoma, found on the trunk of a 51-year-old man. The tumor, measuring 4 cm in maximum diameter and located in the reticular dermis and subcutaneous tissue, was composed of a conglomerate of multiple myxomatous nodules with mucinous stroma and stellate cells. Thin-walled blood vessels were prominent. The histologic examination also revealed abortive hair follicles radiating from the wall of a keratin-filled cyst. Immunohistologically, the stromal cells were positive for vimentin but negative for S-100, smooth muscle a-actin, and desmin. With these findings, the diagnosis of superficial angiomyxoma with trichofolliculoma was made.
我们报告一例发生于一名51岁男性躯干的浅表血管黏液瘤合并毛囊瘤。肿瘤最大直径为4 cm,位于网状真皮层和皮下组织,由多个黏液瘤性结节聚集而成,伴有黏液样基质和星状细胞。薄壁血管明显。组织学检查还发现从充满角蛋白的囊肿壁发出的发育不全的毛囊。免疫组织化学检查显示,基质细胞波形蛋白阳性,但S-100、平滑肌α-肌动蛋白和结蛋白阴性。根据这些发现,诊断为浅表血管黏液瘤合并毛囊瘤。