Bayraktar Ulas Darda, Dufresne Alix, Bayraktar Soley, Purcell Roland Royston, Ajah Ofem Ibiah
Division of Hematology and Oncology, Sylvester Comprehensive Cancer Center, Miami, FL, USA.
J Med Case Rep. 2008 Sep 8;2:292. doi: 10.1186/1752-1947-2-292.
Atrial fibrillation was previously reported in patients with esophageal cancer as a complication of total esophagectomy or photodynamic therapy. Here, we propose that atrial fibrillation may also be caused by external compression of the left atrium by esophageal cancer.
We present a 58-year-old man who developed atrial fibrillation with rapid ventricular rate in the emergency room while being evaluated for dysphagia and weight loss. Atrial fibrillation lasted less than 12 hours and did not recur. Echocardiogram did not reveal any structural heart disease. A 10-cm, ulcerated mid-esophageal mass was seen during esophagogastroscopy. Microscopic examination showed squamous cell carcinoma. Computed tomography of the chest revealed esophageal thickening compressing the left atrium.
External compression of the left atrium was previously reported to provoke atrial fibrillation. Similarly, esophageal cancer may precipitate atrial fibrillation by mechanical compression of the left atrium or pulmonary veins, triggering ectopic beats in susceptible patients.
既往有报道称,心房颤动是食管癌患者行全食管切除术或光动力治疗后的并发症。在此,我们提出心房颤动也可能由食管癌对左心房的外部压迫所致。
我们报告一名58岁男性,因吞咽困难和体重减轻接受评估时,在急诊室发生了心室率快速的心房颤动。心房颤动持续时间不到12小时,未复发。超声心动图未发现任何结构性心脏病。食管胃镜检查发现一个10厘米长、位于食管中段的溃疡性肿物。显微镜检查显示为鳞状细胞癌。胸部计算机断层扫描显示食管增厚压迫左心房。
既往有报道称左心房外部压迫可诱发心房颤动。同样,食管癌可能通过机械性压迫左心房或肺静脉,在易感患者中触发异位搏动,从而引发心房颤动。