一种北甲基碳硼烷嘌呤霉素类似物及其二核苷酸衍生物的全合成。
Total syntheses of a North methanocarba puromycin analog and its dinucleotide derivative.
作者信息
Michel Benoît Y, Strazewski Peter
机构信息
Laboratoire de Synthèse de Biomolécules, Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (UMR 5246), Université Claude Bernard Lyon 1, 69622, Villeurbanne, France.
出版信息
Nucleic Acids Symp Ser (Oxf). 2008(52):559-60. doi: 10.1093/nass/nrn283.
PMID:18776502
Abstract
North methanocarba Puromycin analog 5 and its di-nucleotide derivative 6 were synthesized from D-ribose in respectively 18 and 19 steps, in order to be tested for peptidyl transfer efficiency in ribosomes.
摘要
北甲碳霉素嘌呤霉素类似物5及其二核苷酸衍生物6由D-核糖分别经18步和19步合成，以便测试其在核糖体中的肽基转移效率。
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