Crown ether ring-fused nucleosides: synthesis and conformational properties.
作者信息
Coppola Cinzia, D'Onofrio Jennifer, Di Fabio Giovanni, De Napoli Lorenzo, Montesarchio Daniela
机构信息
Dipartimento di Chimica Organica e Biochimica, Università degli Studi di Napoli Federico II, Complesso Universitario di Monte S. Angelo, via Cinthia, Napoli, Italy.
出版信息
Nucleic Acids Symp Ser (Oxf). 2008(52):667-8. doi: 10.1093/nass/nrn337.
PMID:18776556
Abstract
We here describe the synthesis of a series of novel bicyclic ribonucleoside derivatives, with 18-crown-6 ether moieties attached via their ribose 2- and 3- positions, as first examples of crown ether ring-fused nucleosides, to be evaluated as antiviral and/or antitumoral agents.
摘要
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