扩散加权成像在鉴别转移性与非转移性淋巴结中的可行性：早期经验
Feasibility of diffusion-weighted imaging in the differentiation of metastatic from nonmetastatic lymph nodes: early experience.
作者信息
Kim Jeong Kon, Kim Kyoung Ah, Park Bum-Woo, Kim Namkug, Cho Kyoung-Sik
机构信息
Department of Radiology, Research Institute of Radiology, Medical Imaging Laboratory, Asan Medical Center, University of Ulsan College of Medicine [corrected] Seoul, South Korea.
出版信息
J Magn Reson Imaging. 2008 Sep;28(3):714-9. doi: 10.1002/jmri.21480.
PURPOSE
To investigate the feasibility of diffusion-weighted imaging (DWI) in the differentiation of metastatic from nonmetastatic lymph nodes.
MATERIALS AND METHODS
In 125 patients who underwent lymph node dissection for uterine cervical cancer, DWI was performed at b value of 0 and 1000 s/mm2. By referring to the surgical maps of the pelvic lymph nodes, the apparent diffusion coefficient (ADC) was compared in the metastatic and nonmetastatic lymph nodes, and receiver-operating-characteristics analysis was performed to evaluate the diagnostic performance of the ADC in differentiating metastatic from nonmetastatic lymph nodes.
RESULTS
The ADC were significantly lower in the metastatic lymph nodes (0.7651x10(-3) mm2/s+/-0.1137) than in the nonmetastatic lymph nodes (1.0021x10(-3) mm2/s+/-0.1859; P<0.001). The area-under-the-curve of ADC for differentiating metastatic from nonmetastatic lymph nodes, was 0.902. The sensitivity and specificity of ADC for differentiating metastatic from nonmetastatic lymph nodes, were 87% for the ADC and 80%, respectively.
CONCLUSION
DWI is feasible for differentiating metastatic from nonmetastatic lymph nodes in patients with uterine cervical cancer.
目的
探讨扩散加权成像（DWI）在鉴别转移性与非转移性淋巴结中的可行性。
材料与方法
对125例行宫颈癌淋巴结清扫术的患者，在b值为0和1000 s/mm²时进行DWI检查。参照盆腔淋巴结手术图谱，比较转移性和非转移性淋巴结的表观扩散系数（ADC），并进行受试者操作特征分析，以评估ADC在鉴别转移性与非转移性淋巴结中的诊断性能。
结果
转移性淋巴结的ADC（0.7651×10⁻³ mm²/s±0.1137）显著低于非转移性淋巴结（1.0021×10⁻³ mm²/s±0.1859；P<0.001）。ADC鉴别转移性与非转移性淋巴结的曲线下面积为0.902。ADC鉴别转移性与非转移性淋巴结的敏感性和特异性分别为87%和80%。
结论
DWI在鉴别宫颈癌患者转移性与非转移性淋巴结方面是可行的。
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