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泌尿生殖系统结核:根据临床和影像学表现将患者分为七个不同组。

Urogenital tuberculosis: patient classification in seven different groups according to clinical and radiological presentation.

作者信息

Figueiredo Andre A, Lucon Antonio M, Gomes Cristiano M, Srougi Miguel

机构信息

Division of Urology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil.

出版信息

Int Braz J Urol. 2008 Jul-Aug;34(4):422-32; discussion 432. doi: 10.1590/s1677-55382008000400004.

Abstract

PURPOSE

To describe and classify 80 cases of urogenital tuberculosis in seven groups of similar clinical and radiological presentation.

MATERIALS AND METHODS

80 patients (56 males, 70%; median age 34 years; age range 12 to 75) with urogenital tuberculosis were retrospectively reviewed. The patients were divided in seven groups: 1) Bilateral parenchymatous renal lesions; 2) No or minimal changes on radiographic examination; 3) Unilateral renal tuberculosis; 4) Contracted bladder; 5) Contracted bladder with renal failure; 6) Tuberculosis on a transplanted kidney; 7) Isolated genital tuberculosis.

RESULTS

  1. Seven (8.8%) patients had multiple bilateral parenchymatous renal lesions with fever and malaise, characteristic of miliary tuberculosis. Three of these patients had AIDS. 2) Six (7.5%) cases had an early diagnosis, with minimal or no radiographic lesions. Two did not have any urologic symptoms. 3) Twelve (15%) patients had unilateral renal tuberculosis with partial (1 case) or total non-function kidney. 4) Thirty-seven (46.3%) patients had contracted bladder associated with unilateral partial (1 case) or total non-function kidney. 5) Ten (12.5%) patients had end stage renal disease due to tuberculosis with contracted bladder. 6) Four (5.0%) patients had tuberculosis on a transplanted kidney, with graft loss in half the cases. 7) Four (5.0%) patients had prostate or epididymis tuberculosis without associated renal lesion.

CONCLUSIONS

Urogenital tuberculosis is a destructive disease of the urogenital tract with variable clinical and radiographic presentation. A classification according to similar patterns correlating with disease stage is feasible although early diagnosis is the only prevention of the most severe forms.

摘要

目的

对80例具有相似临床和放射学表现的泌尿生殖系统结核病例进行描述并分组。

材料与方法

对80例泌尿生殖系统结核患者(56例男性,占70%;中位年龄34岁;年龄范围12至75岁)进行回顾性研究。患者被分为七组:1)双侧肾实质病变;2)影像学检查无或仅有轻微改变;3)单侧肾结核;4)膀胱挛缩;5)膀胱挛缩伴肾衰竭;6)移植肾结核;7)孤立性生殖器结核。

结果

1)7例(8.8%)患者有双侧多发肾实质病变,伴有发热和不适,为粟粒性结核的特征。其中3例患者患有艾滋病。2)6例(7.5%)病例早期诊断,影像学病变轻微或无病变。2例无任何泌尿系统症状。3)12例(15%)患者有单侧肾结核,伴有部分(1例)或完全无功能肾。4)37例(46.3%)患者有膀胱挛缩,伴有单侧部分(1例)或完全无功能肾。5)10例(12.5%)患者因结核导致终末期肾病并伴有膀胱挛缩。6)4例(5.0%)患者有移植肾结核,半数病例移植肾丢失。7)4例(5.0%)患者有前列腺或附睾结核,无相关肾病变。

结论

泌尿生殖系统结核是一种泌尿生殖道的破坏性疾病,临床和放射学表现多样。根据与疾病阶段相关的相似模式进行分类是可行的,尽管早期诊断是预防最严重形式的唯一方法。

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