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[环甲膜上部分喉切除术作为初次行垂直部分喉切除术治疗后复发性喉癌的挽救性手术。病例报告]

[Supracricoid partial laryngectomy as salvage for recurrent carcinoma of the larynx initially treated by vertical partial hemilaryngectomy. Case report].

作者信息

Luna-Ortiz Kuauhyama, Nuñez-Valencia Ethel Ruth, Carmona-Luna Tania

机构信息

Departamento de Cirugía de Cabeza y Cuello, Instituto Nacional de Cancerología, México, D.F.

出版信息

Cir Cir. 2008 Jul-Aug;76(4):333-7.

Abstract

OBJECTIVE

We undertook this study to report the possibility of salvage of vertical partial hemilaryngectomy with imbrication laryngoplasty (PVHLIL) to supracricoid partial laryngectomy (SCPL) with cricohyoidoepiglottopexy (CHEP) in a patient with recurrent glottic carcinoma.

CLINICAL CASE

A 68-year-old patient with recurrent glottic squamous cell carcinoma (T1aN0) was treated with imbricated partial laryngectomy. Transoperative histopathological report demonstrated vocal cord free surgical margins anterior at 1 cm and 0.4 cm posterior. The patient was evaluated trimonthly and at 16-month follow-up presented with tumor activity on the posterior third of the left false vocal cord, close to the arytenoids, which still conserved mobility. Biopsy was performed and confirmed recurrence of squamous cell carcinoma. SCPL with CHEP was performed with a satisfactory postoperative evolution with tracheotomy decannulation at day 7. Physiological phonation and retirement of nasogastric tube were accomplished at day 15, as well as reinitiation of oral feeding. Histopathological report showed a moderately differentiated squamous cell carcinoma. Functional evaluation with PVHLIL is a clear voice alteration; however, patients do not require permanent tracheostomy, and a close to normal biopsicosocial integration after SCPL + CHEP is possible.

CONCLUSIONS

PVHLIL is an excellent treatment option for selected glottic tumors staged T1 or T2. Close follow-up must be given to allow the possibility of organ conservation either with radiotherapy or surgery. When recurrence occurs, SCPL + CHEP must be considered according to the established criteria for this procedure. Total laryngectomy must be considered as the last option, with the only purpose being a normal quality of life.

摘要

目的

我们开展这项研究,旨在报告对于一名复发性声门癌患者,能否将垂直部分喉切除术加叠瓦状喉成形术(PVHLIL)挽救性手术转换为环状软骨上部分喉切除术加环状软骨舌骨会厌固定术(SCPL + CHEP)。

临床病例

一名68岁复发性声门鳞状细胞癌(T1aN0)患者接受了叠瓦状部分喉切除术。术中组织病理学报告显示,声带前切缘距肿瘤1 cm,后切缘距肿瘤0.4 cm,切缘无肿瘤残留。对该患者每三个月进行一次评估,在16个月的随访中,发现左室带后部三分之一靠近杓状软骨处有肿瘤活动,杓状软骨仍保留活动度。进行活检,确诊为鳞状细胞癌复发。遂行SCPL + CHEP手术,术后恢复良好,术后第7天气管切开插管拔除。术后第15天实现生理性发声,拔除鼻胃管,并重新开始经口进食。组织病理学报告显示为中分化鳞状细胞癌。PVHLIL术后功能评估显示声音明显改变;然而,患者无需永久性气管造口,SCPL + CHEP术后有可能实现接近正常的生物心理社会融合。

结论

PVHLIL是治疗T1或T2期特定声门肿瘤的极佳选择。必须密切随访,以便有可能通过放疗或手术保留器官。当复发发生时,应根据该手术既定标准考虑行SCPL + CHEP。全喉切除术必须作为最后的选择,唯一目的是保证正常生活质量。

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